T6576

L-Theanin

• Synonym(e): N_γ-Ethyl-L-glutamin
• Empirische Formel (Hill-System): C₇H₁₄N₂O₃
• CAS-Nummer: 3081-61-6
• Molekulargewicht: 174.20
• UNSPSC Code: 12352200
• PubChem Substance ID: 24900389
• EC Number: 221-379-0
• MDL number: MFCD00059653

Eigenschaften

• SMILES string: CCNC(=O)CC[C@H](N)C(O)=O
• InChI: 1S/C7H14N2O3/c1-2-9-6(10)4-3-5(8)7(11)12/h5H,2-4,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1
• InChI key: DATAGRPVKZEWHA-YFKPBYRVSA-N

Beschreibung

Biochem/physiol Actions

Theanine is able to bind to AMPA, kainite, and NMDA glycine receptors in rat cortical neurons but with less affinity than glutamic acid. It has been studied as a glutamate transport inhibitor, preventing glutamate uptake by M5076 ovarian sarcoma-bearing mouse cells and increasing the effect of doxorubicin on tumor growth in M5076 mice.

Other Notes

Theanine is an amino acid analog of glutamine, found in green tea.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H317
• Sicherheitshinweise: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Lagerklasse: 11 - Combustible Solids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): dust mask type N95 (US), Eyeshields, Faceshields, Gloves