1000818

Abirateronacetat

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): 17-(Pyridin-3-yl)-androsta-5,16-dien-3β-yl-acetat
• Empirische Formel (Hill-System): C₂₆H₃₃NO₂
• CAS-Nummer: 154229-18-2
• Molekulargewicht: 391.55
• NACRES: NA.24
• PubChem Substance ID: 329748877
• UNSPSC Code: 41116107
• MDL number: MFCD00934213
• eCl@ss: 25140904

Eigenschaften

• grade: pharmaceutical primary standard
• agency: USP
• API family: abiraterone
• manufacturer/tradename: USP
• application(s): pharmaceutical; pharmaceutical; pharmaceutical (small molecule)
• format: neat
• SMILES string: C[C@]12C(C[C@@H](OC(C)=O)CC2)=CC[C@]3([H])[C@]1([H])CC[C@@]4(C)[C@@]3([H])CC=C4C5=CC=CN=C5
• InChI: 1S/C26H33NO2/c1-17(28)29-20-10-12-25(2)19(15-20)6-7-21-23-9-8-22(18-5-4-14-27-16-18)26(23,3)13-11-24(21)25/h4-6,8,14,16,20-21,23-24H,7,9-13,15H2,1-3H3/t20-,21-,23-,24-,25-,26+/m0/s1
• InChI key: UVIQSJCZCSLXRZ-UBUQANBQSA-N
• Gene Information: human ... CYP17A1(1586)

Beschreibung

General description

Find answers to frequently asked questions on USP products in USP FAQs.

Abiraterone acetate is a pro-drug of abiraterone and a potent inhibitor of the enzyme CYP17, required for androgen biosynthesis in the adrenal glands, testes and prostate tissue.

Application

Abiraterone acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Abiraterone Acetate Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS08,GHS09
• Signalwort: Danger
• Gefahrencodes: H360F,H373,H410
• Sicherheitshinweise: P202 - P260 - P273 - P280 - P308 + P313 - P391
• Hazard Classifications: Aquatic Chronic 1 - Repr. 1B - STOT RE 2
• Zielorgane: Endocrine system
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable