1235274

Enalaprilat

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): Enalaprilat Dihydrat, (2S)-1-[(2S)-2-[[(1S)-1-Carboxy-3-phenyl-propyl]-amino]-propanoyl]-pyrrolidin-2-carbonsäure
• Empirische Formel (Hill-System): C₁₈H₂₄N₂O₅ ·2H₂O
• CAS-Nummer: 84680-54-6
• Molekulargewicht: 384.42
• NACRES: NA.24
• PubChem Substance ID: 329749718
• UNSPSC Code: 41116107
• MDL number: MFCD00941393

Eigenschaften

• grade: pharmaceutical primary standard
• agency: USP
• API family: enalaprilat
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule); pharmaceutical
• format: neat
• SMILES string: O.O.C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O
• InChI: 1S/C18H24N2O5.2H2O/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13;;/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25);2*1H2/t12-,14-,15-;;/m0../s1
• InChI key: MZYVOFLIPYDBGD-MLZQUWKJSA-N
• Gene Information: human ... ACE(1636)

Beschreibung

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Enalaprilat USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Enalapril Maleate and Hydrochlorothiazide Tablets
• Enalapril Maleate Tablets
• Enalaprilat
• Enalaprilat Injection

Biochem/physiol Actions

Enalaprilat is an inhibitor of angiotensin converting enzyme (ACE), antihypertensive, and a Bradykinin B1 receptor activator.

Enalaprilat is an inhibitor of angiotensin converting enzyme (ACE), antihypertensive, and a Bradykinin B1 receptor activator. Enalaprilat has nM potency versus ACE and also activates B1 receptors to release NO.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable