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1502508

USP

Penicillin-G-kalium

Name: Penicillin-G-kalium
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

Penicillin G Kaliumsalz, Benzylpenicillin Kaliumsalz

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Über diesen Artikel

Empirische Formel (Hill-System):

C₁₆H₁₇KN₂O₄S

CAS-Nummer:

113-98-4

Molekulargewicht:

372.48

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329750683

MDL number:

MFCD00036193

Beilstein/REAXYS Number:

3832841

eCl@ss:

25140904

Technischer Dienst

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Unterstützung erhalten

Eigenschaften

grade

pharmaceutical primary standard

agency

USP

API family

penicillin & derivatives

form

powder

manufacturer/tradename

USP

application(s)

USP Biologics
pharmaceutical
pharmaceutical (small molecule)

format

neat

SMILES string

[K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

InChI

1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

InChI key

IYNDLOXRXUOGIU-LQDWTQKMSA-M

Beschreibung

General description

Find answers to frequently asked questions on USP products in USP FAQs.

Penicillin G potassium is a natural β-lactam antibiotic that targets bacterial cell wall synthesis by inhibiting transpeptidase enzymes. It is effective against non-β-lactamase-producing Gram-positive organisms. The USP standard facilitates microbiological potency tests and purity analysis.

The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Penicillin G potassium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Penicillamine
Penicillin G Benzathine
Penicillin G Benzathine and Penicillin G Procaine Injectable Suspension
Penicillin G Benzathine Injectable Suspension
Penicillin G Potassium
Penicillin G Potassium for Injection
Penicillin G Potassium for Oral Solution

Biochem/physiol Actions

Wirkungsweise: Penicillin G wirkt durch Hemmung der Zellwandsynthese durch die Bindung an Penicillin bindende Proteine (PBP), um die Vernetzung der Peptidoglycan-Kette zu hemmen.

Antimikrobielles Spektrum: Diese Produkt ist wirksam gegen grampositive und gramnegative Bakterien.