1535008

Phenytoin

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): 5,5-Diphenylhydantoin, 5,5-Diphenyl-2,4-imidazolidindion, Phenytoin
• Empirische Formel (Hill-System): C₁₅H₁₂N₂O₂
• CAS-Nummer: 57-41-0
• Molekulargewicht: 252.27
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329750826
• MDL number: MFCD00005264
• Beilstein/REAXYS Number: 384532
• eCl@ss: 25140904

Eigenschaften

• grade: pharmaceutical primary standard
• agency: USP
• API family: phenytoin
• manufacturer/tradename: USP
• mp: 293-295 °C (lit.)
• application(s): pharmaceutical (small molecule); pharmaceutical
• format: neat
• SMILES string: O=C1NC(=O)C(N1)(c2ccccc2)c3ccccc3
• InChI: 1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)
• InChI key: CXOFVDLJLONNDW-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335) ;

Beschreibung

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Phenytoin USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Phenytoin Sodium
• Phenytoin Chewable Tablets
• Phenytoin Oral Suspension
• Phenytoin Sodium Injection
• Extended Phenytoin Sodium Capsules
• Phenytoin Compounded Topical Gel
• Fosphenytoin Sodium Injection

Biochem/physiol Actions

Antikonvulsivum

Verringert die Inzidenz von tonisch-klonischen Krampfanfällen; scheint erregbare Membranen, vermutlich durch Effekte auf Na⁺-, K⁺- und Ca²⁺Kanäle, zu stabilisieren.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Disclaimer

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Danger
• Gefahrencodes: H302,H351,H360FD
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Repr. 1B
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Sicherheitshinweise: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405