Synthesis and free radical scavenging activity of some new spiropyranocoumarins.

Synthesis and free radical scavenging activity of some new spiropyranocoumarins.

Bioorganic & medicinal chemistry letters (2008-10-07)

Vassiliki Panteleon, Ioannis K Kostakis, Panagiotis Marakos, Nicole Pouli, Ioanna Andreadou

ZUSAMMENFASSUNG

A series of novel spiro-substituted 4-hydroxypyranocoumarins and their corresponding dihydropyrano cis-diols has been synthesized. Among them the spiroadamantylpyranocoumarin and the diols can interact with the stable free radical 1,1-diphenyl-2-picrylhydrazyl and scavenge superoxide anions generated in the xanthine-xanthine oxidase system.

MATERIALIEN

Produktnummer

Marke

Produktbeschreibung

B1378

Sigma-Aldrich

2,6-Di-tert-butyl-4-Methylphenol, ≥99.0% (GC), powder

Preise und Verfügbarkeit sind derzeit nicht verfügbar.

W218405

Sigma-Aldrich

Butyliertes Hydroxytoluol, ≥99%, FCC, FG

Preise und Verfügbarkeit sind derzeit nicht verfügbar.