Skip to Content
Merck

OLIGO

Custom DNA Oligos

Design and Order Custom Oligos

Synonym(s):

Custom DNA Oligos, DNA, DNA primer, High-throughput DNA, ISO 13485 Oligos, Locked Nucleic Acid oligos, Modified oligos, NGS adapters, NGS−grade oligos, Next−generation sequencing adapters, Next−generation sequencing oligos, Oligonucleotide, Oligonucleotides, Oligos, Oligos in plates, cGMP Oligos

Slide 1 of 1
Sign In to View Organizational & Contract Pricing

About This Item

UNSPSC Code:
41105327

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

      

Standard DNA Oligos

  • Scale: 0.025, 0.05, 0.2, 1.0, 10, and 15 μmol
  • Purification: Desalt, Cartridge, HPLC, and PAGE
  • Sequence Length: Up to 120 bases
  • Modifications: Over 200 available, including dyes (fluorescent and non-fluorescent)
  • Quality Control: 100% Mass Spectrometry
  • Format: Supplied dry or in solution – tubes, plates and mixed plates (forward and reverse primers)
  • WellRED Oligos: Available
  • qPCR Probes: Available
  • Learn more about Standard DNA Synthesis

Tubes

Order

Plates

Order

Easy Oligo

  • Amount: 3 OD
  • Concentration: 100 µM
  • Purification: Desalt
  • Sequence Length: 15 - 30 bases
  • Modifications: Not available
  • Quality Control: 100% Mass Spectrometry
  • Format: Supplied in solution
  • Ships within 24 hours of order receipt
  • Learn more

Tubes

Order

Pure & Simple Primers

  • Amount: 3 OD
  • Purification: Cartridge
  • Sequence Length: 12 - 35 bases
  • Modifications: Not available
  • Quality Control: 100% Mass Spectrometry
  • Format: Supplied dry
  • Ships within 24 hours of order receipt
  • Learn more

Tubes

Order

iScale Oligos™ (mg & g quantity)

  • Larger quantities for in vivo, high throughput and commercial projects
  • Quantity: 10, 25, 50, 100, 250, 500 mg; 1, 2, 5, 10, 15 g
  • Purification: Desalt, RP-HPLC & In vivo treatment
  • Sequence Length: 10 - 55 bases (Inquire for longer lengths)
  • Modifications: 6-FAM, Biotin, Phosphate, Amino-Modifiers & others
  • Quality Control: 100% Mass Spectrometry
  • Format: Supplied dry
  • Services: Salt Exchange, Filtration & Endotoxin Testing
  • Learn more

Tubes

Order

Next-Gen Sequencing Oligos

  • Custom universal and index (barcode) adapter oligos for major sequencing platforms
  • Suitable purity (percent full-length sequence) to maintain sequence read integrity
  • Low levels of cross-contamination to facilitate proper sequence assembly
  • Learn more
Order

Commercial Oligos

  • Custom DNA Primers, qPCR Probes, and Next-Gen Sequencing Oligos for Life Science Research Tools, Molecular Diagnostics (MDx), and Laboratory Developed Tests (LDTs)
  • Component or complete kit manufacturing, including custom formulations, packaging, and private labeling
  • Learn more
Quotation

GMP OLIGOS

  • Custom cGMP Oligos, available with custom specifications, are Commercial Oligos (raw materials) for MDx and LDTs
  • Learn more
Quotation

Locked Nucleic Acid

  • Available with Custom DNA Oligos
  • Increased thermal stability and hybridization specificity
  • Easier and more specific designs for problematic target sequences
  • Learn more

Tubes

Order
Sign In To Continue

To continue reading please sign in or create an account.

Don't Have An Account?

related product

Product No.
Description
Pricing
Fuqiang Chen et al.
Nature methods, 8(9), 753-755 (2011-07-19)
Zinc-finger nucleases (ZFNs) have enabled highly efficient gene targeting in multiple cell types and organisms. Here we describe methods for using simple ssDNA oligonucleotides in tandem with ZFNs to efficiently produce human cell lines with three distinct genetic outcomes: (i)
T N Wiegner et al.
Marine pollution bulletin, 114(2), 952-961 (2016-11-22)
Spatial and temporal patterns of coastal microbial pollution are not well documented. Our study examined these patterns through measurements of fecal indicator bacteria (FIB), nutrients, and physiochemical parameters in Hilo Bay, Hawai'i, during high and low river flow. >40% of
Leonel Armas-López et al.
Oncotarget, 8(40), 67056-67081 (2017-10-06)
Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic responses in lung cancer patients; however, the mechanisms involved in these responses have yet to be
Eun Jung Thak et al.
Journal of microbiology (Seoul, Korea), 56(1), 11-23 (2018-01-05)
Protein glycosylation, the most universal and diverse post-translational modification, can affect protein secretion, stability, and immunogenicity. The structures of glycans attached to proteins are quite diverse among different organisms and even within yeast species. In yeast, protein glycosylation plays key
Chong He et al.
PLoS genetics, 10(12), e1004860-e1004860 (2014-12-19)
The common non-steroidal anti-inflammatory drug ibuprofen has been associated with a reduced risk of some age-related pathologies. However, a general pro-longevity role for ibuprofen and its mechanistic basis remains unclear. Here we show that ibuprofen increased the lifespan of Saccharomyces
View All Related Papers

Articles

Locked Nucleic Acid & Minor Groove Binder / Eclipse Dark Quencher

Explore Locked Nucleic Acid and MGB. These oligo modifications offer stability and specificity in molecular analysis, making them ideal for research and diagnostic applications.

OligoEvaluator™ for Tm Calculation & Primer Analysis

We offer an easy-to-use Oligo Analyzer tool, OligoEvaluator™ that provides better primer dimer analysis values for PCR, and serves as an online oligonucleotide sequence calculator and Tm calculator.

Custom Oligos Modifications

We offer over 200 custom DNA oligos modification for both DNA, RNA oligonucleotides and sequencing to probes for gene.

Protocols

Plant-Based PCR Inhibitors & Master Mix Performance

Evaluate PCR inhibitors and enzyme selection using GenElute™-E Single Spin Plant Extraction Kit, KOD-One™ PCR Master Mix, and competitors.

Related Content

Custom Oligos for Commercial Use

As the world’s leading supplier of oligonucleotides, Sigma-Aldrich delivers the largest portfolio of expertise to its diagnostic partners. ISO 13485 & cGMP/ASR certified.

OligoArchitect™ Consultative

For more complex and demanding applications, utilize our consultative service to ensure the success of your assay.

Oligonucleotide FAQ

Custom oligonucleotide synthesis service FAQs address common queries on DNA and RNA molecule synthesis.

Pure & Simple Primers

Oligo synthesis technology delivers high-quality products for research applications with full-length purity.

See All

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service