L-Aspartic acid is soluble in water at 5 mg/mL.
A7219
Acide L-aspartique
from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%
Synonyme(s) :
Acide (S)-(+)-aminosuccinique, Acide (S)-aminobutanedioïque
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100 G
52,10 €
1 KG
281,00 €
52,10 €
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A propos de cet article
Formule linéaire :
HO2CCH2CH(NH2)CO2H
Numéro CAS:
Poids moléculaire :
133.10
NACRES:
NA.75
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-291-6
MDL number:
Beilstein/REAXYS Number:
1723530
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Laissez-nous vous aiderNom du produit
Acide L-aspartique, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%
InChI key
CKLJMWTZIZZHCS-REOHCLBHSA-N
InChI
1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
SMILES string
N[C@@H](CC(O)=O)C(O)=O
biological source
non-animal source
agency
meets EP testing specifications
meets USP testing specifications
assay
98.5-101.0%
form
powder
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
color
white to off-white
mp
>300 °C (dec.) (lit.)
solubility
1 M HCl: 100 mg/mL
Quality Level
Gene Information
human ... CA1(759), CA2(760)
rat ... Grin2a(24409)
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Cet article | 11189 | A5474 | PHR1104 |
|---|---|---|---|
| form powder | form powder or crystals | form crystalline powder | form - |
| technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) cell culture | mammalian: suitable | technique(s) HPLC: suitable, gas chromatography (GC): suitable |
| assay 98.5-101.0% | assay ≥99.5% (T) | assay ≥98.5% | assay - |
| impurities endotoxin, tested | impurities insoluble matter, passes filter test, ≤0.3% foreign amino acids | impurities endotoxin, heavy metals, trace metals, residual solvents, tested | impurities - |
| solubility 1 M HCl: 100 mg/mL | solubility 1 M HCl: 0.5 M at 20 °C, clear, colorless | solubility 1 M HCl: 50 mg/mL | solubility - |
| Quality Level 300 | Quality Level 200 | Quality Level 400 | Quality Level 300 |
Biochem/physiol Actions
Principal neurotransmetteur de l'excitation synaptique rapide.
Application
L-Aspartic acid has been used:
- as an aspartame (ASP) metabolite to determine acetylcholinesterase (AChE) activity in the hippocampal homogenate of suckling rats[1]
- as printed chemotaxis ligands to screen chemotaxis receptors with high-throughput technologies and verify the interactions with surface plasmon resonance (SPR) and nuclear magnetic resonance (NMR)[2]
- as a supplement in Dulbecco′s modified Eagle′s medium (DMEM) for supplementation assays of various cultured cell lines[3]
General description
Classe de stockage
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Amino acid production
Eggeling L and Sahm H
Comprehensive Biotechnology (2011)
Aspartic acid
Johnson EC
reference module in biomedical sciences (2017)
Christopher J Day et al.
Methods in molecular biology (Clifton, N.J.), 1512, 51-63 (2016-11-26)
Despite many years of research into bacterial chemotaxis, the only well characterized system to date is that of E. coli. Even for E. coli, the direct ligand binding had been fully characterized only for aspartate and serene receptors Tar and
Hongyu Ding et al.
Science advances, 7(47), eabk1023-eabk1023 (2021-11-18)
[Figure: see text].
Thomas Bertero et al.
Cell metabolism, 29(1), 124-140 (2018-10-09)
Dysregulation of extracellular matrix (ECM) deposition and cellular metabolism promotes tumor aggressiveness by sustaining the activity of key growth, invasion, and survival pathways. Yet mechanisms by which biophysical properties of ECM relate to metabolic processes and tumor progression remain undefined.
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