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Merck

CAV1

caveolin 1, caveolae protein, 22kDa

Sinonimi:
BSCL3, CGL3, MSTP085, PPH3, VIP21
Specie:
ID UniProtKB:
ID gene:
  • Human(857) Summary: The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]
  • Mouse(12389) caveolin 1, caveolae protein
  • Rat(25404) caveolin 1, caveolae protein
  • naked mole-rat(101726366) caveolin 1, caveolae protein, 22kDa
  • domestic guinea pig(100718512) caveolin 1, caveolae protein, 22kDa
  • chicken(373996) caveolin 1, caveolae protein, 22kDa
  • dog(403980) caveolin 1, caveolae protein, 22kDa
  • domestic cat(493668) caveolin 1, caveolae protein, 22kDa
  • Horse(100055975) caveolin 1, caveolae protein, 22kDa
  • Goat(100860749) caveolin 1, caveolae protein, 22kDa
  • cow(281040) caveolin 1, caveolae protein, 22kDa
  • sheep(445468) caveolin 1, caveolae protein, 22kDa
  • Domestic Rabbit(100008837) caveolin 1, caveolae protein, 22kDa
  • domestic guinea pig(100135639) caveolin 1, caveolae protein
  • Zebrafish(323695) caveolin 1

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-CAV1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-CAV1 antibody produced in rabbit, purified antibody, Protein A purified,
Reattività con
bovine, dog, horse, human, mouse, pig, rabbit, rat, sheep
Applicazione
immunohistochemistry
western blot
Anti-Caveolin-1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence

western blot
Anti-CAV1 (Ab-14) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
western blot
Anti-phospho-Caveolin-1 (Ser37), from rabbit, purified by affinity chromatography,
Reattività con
human, mouse, rat
Applicazione
inhibition assay
western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human CAV1,
Specie
human
MISSION® esiRNA, targeting mouse Cav1,
Specie
mouse