C4396
Carbonic Anhydrase I from human erythrocytes
Sinonimo/i:
Carbonate Dehydratase, Carbonate Hydrolyase, Carbonic Anhydrase Isozyme I
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Cambia visualizzazione
| Voi/SKU | Disponibilità | Prezzo |
|---|---|---|
1 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 148.00 |
5 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 298.00 |
25 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 1610.00 |
Informazioni su questo articolo
Numero CAS:
UNSPSC Code:
12352204
NACRES:
NA.25
EC Number:
232-576-6
MDL number:
Numero CE:
Specific activity:
100-500 W-A units/mg protein
Servizio Tecnico
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Permettici di aiutartiApplication
Carbonic anhydrase from human erythrocytes (HCA) has been used to study the molten-globule state of carbonic anhydrase (CA). Chaperone-like α-crystallin binds to this state of the enzyme and prevents its aggregation. The enzyme from sigma has been used for the analysis of thermodynamic stability of the enzyme. Furthermore, its clinical significance has been evaluated in human non-small cell lung cancer.
Biochem/physiol Actions
Carbonic anhydrase is a zinc metalloenzyme that has a molecular weight of approximately 30,000 Da. The enzyme catalyzes the hydration of carbon dioxide to carbonic acid. It is involved in vital processes such as pH and CO2 homeostasis, transport of bicarbonate and CO2, biosynthetic reactions, bone resorption, calcification, and tumorigenicity. Therefore, this enzyme is an important target for inhibitors with clinical applications in various pathologies such as glaucoma, epilepsy and Parkinson′s disease.
Preparation Note
chromatographically
purified.
purified.
Other Notes
One Wilbur-Anderson (W-A) unit will cause the pH of a 0.02 M Trizma buffer to drop from 8.3 to 6.3 per min at 0 °C. (One W-A unit is essentially equivalent to one Roughton-Booth unit.)
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Questo articolo | |||
|---|---|---|---|
| description - | description Isoelectric focusing marker, pI 6.6 | description BioReagent, suitable for GFC marker | description ≥95% (SDS-PAGE), ≥3,000 W-A units/mg protein, lyophilized powder |
| specific activity 100-500 W-A units/mg protein | specific activity - | specific activity - | specific activity ≥3,500 W-A units/mg protein |
| Gene Information human ... CA1(759) | Gene Information - | Gene Information - | Gene Information - |
| form powder | form powder | form powder | form lyophilized powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C |
| UniProt accession no. | UniProt accession no. - | UniProt accession no. - | UniProt accession no. - |
| mol wt 30 kDa | mol wt - | mol wt ~29,000 | mol wt - |
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Parola di avvertenza
Danger
Codici di pericolo
Avvertenze di sicurezza
Hazard Classifications
Resp. Sens. 1
Classe di stoccaggio
11 - Combustible Solids
WGK
WGK 3
Punto di infiammabilità (°F)
Not applicable
Punto di infiammabilità (°C)
Not applicable
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