E3263

Efaroxan hydrochloride

≥98% (HPLC)

• Sinonimo/i: 2-Ethyl-2-(imidazolin-2-yl)-2,3-dihydrobenzofuran hydrochloride, RX 821037A
• Formula empirica (notazione di Hill): C₁₃H₁₆N₂O · HCl
• Numero CAS: 89197-00-2
• Peso molecolare: 252.74
• NACRES: NA.77
• PubChem Substance ID: 24278415
• UNSPSC Code: 12352200
• MDL number: MFCD00069270
• Assay: ≥98% (HPLC)

Proprietà

• Quality Segment: 100
• assay: ≥98% (HPLC)
• solubility: H₂O: >20 mg/mL
• SMILES string: Cl.CCC1(Cc2ccccc2O1)C3=NCCN3
• InChI: 1S/C13H16N2O.ClH/c1-2-13(12-14-7-8-15-12)9-10-5-3-4-6-11(10)16-13;/h3-6H,2,7-9H2,1H3,(H,14,15);1H
• InChI key: DWOIUCRHVWIHAH-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)

Descrizione

Biochem/physiol Actions

(+)-Isomer is a selective α-adrenoceptor antagonist; (−)-isomer is an imidazoline ligand that induces insulin secretion, mediated by the blockade of ATP-sensitive potassium channels in pancreatic β cells; I₁ imidazoline binding site antagonist.

(+)-Isomer is a selective α-adrenoceptor antagonist; (−)-isomer is an imidazoline ligand; I₁ imidazoline binding site antagonist.

Features and Benefits

This compound is featured on the Imidazoline Binding Sites and Potassium Channels pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informazioni sulla sicurezza

• Pittogrammi: GHS06
• Parola di avvertenza: Danger
• Codici di pericolo: H301
• Avvertenze di sicurezza: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable
• DPI (dispositivi di protezione individuale): Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges