E4375

(−)-epinefrina

solid, adrenergic receptor agonist

• Sinonimo/i: Alcol L-3,4-diidrossi-α-(metilamminometil)benzilico D-idrogeno, L-adrenalina, L-adrenalina D-idrogenotartrato, L-epinefrina D-idrogenotartrato
• Formula empirica (notazione di Hill): C₉H₁₃NO₃ · C₄H₆O₆
• Numero CAS: 51-42-3
• Peso molecolare: 333.29
• NACRES: NA.77
• PubChem Substance ID: 24277774
• UNSPSC Code: 12352200
• EC Number: 200-097-1
• MDL number: MFCD00035077
• Form: solid

Proprietà

• Nome del prodotto: (−)-epinefrina, solid
• form: solid
• Quality Segment: 200
• color: white
• solubility: H₂O: soluble, alcohol: soluble
• storage temp.: 2-8°C
• SMILES string: O[C@H]([C@@H](O)C(O)=O)C(O)=O.CNC[C@H](O)c1ccc(O)c(O)c1
• InChI: 1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1
• InChI key: YLXIPWWIOISBDD-NDAAPVSOSA-N
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), ADRB3(155)

Descrizione

General description

Epinephrine is a hormone, which is also termed as adrenaline. It is a monoamine and catecholamine.

Application

(-)Epinephrine (+)-bitartrate salt has been used:

• to test the possible existence of β-adrenergic vasodilation
• to infuse into the adipose region to minimize blood loss and tissue contamination
• as a platelet agonist in the preparation of optimal platelet aggregometry 96-well plates
• in the measurement of total superoxide dismutase (tSOD) enzymatic activity

Biochem/physiol Actions

Agonista del recettore adrenergico

Epinephrine is mainly liberated from adrenal medulla in response to stress, that is facilitated through sympathetic fibers.

Features and Benefits

This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors, β-Adrenoceptors and Dopamine, Norepinephrine and Epinephrine Synthesis pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Disclaimer

Light sensitive

Informazioni sulla sicurezza

• Pittogrammi: GHS06
• Parola di avvertenza: Danger
• Codici di pericolo: H300
• Avvertenze di sicurezza: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 1 Oral
• Classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Che succede?: WGK 3
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable
• DPI (dispositivi di protezione individuale): Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges