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ED4SS

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate

99.0-102.0% (titration)

Sinonimo/i:

EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate dihydrate

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Voi/SKUDisponibilitàPrezzo
100 g
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CHF 79.50
500 g
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CHF 153.00
1 kg
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CHF 253.00
2.5 kg
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CHF 511.00

Informazioni su questo articolo

Formula condensata:
(NaOOCCH2)2NCH2CH2N(CH2COONa)2 · 2H2O
Numero CAS:
Peso molecolare:
416.20
NACRES:
NA.77
PubChem Substance ID:
EC Number:
200-573-9
Beilstein/REAXYS Number:
3861753
MDL number:
UNSPSC Code:
12352116
eCl@ss:
32150312

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Quality Segment

assay

99.0-102.0% (titration)

form

crystalline

reaction suitability

reagent type: chelator

solubility

H2O: soluble, clear, colorless

SMILES string

O.O.[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.4Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;2*1H2/q;4*+1;;/p-4

InChI key

KSYNLCYTMRMCGG-UHFFFAOYSA-J

General description

Ethylenediaminetetraacetic acid (EDTA) is a polyprotic acid and a metal chelating agent. It comprises four carboxylic acid and two amine groups with lone-pair electrons that can chelate calcium and several other metal ions. 

Application

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate has been used:
  • in the decalcification of femurs for the histoprocessing and staining of osteochondral tissue
  • as a component of NH4Cl lysis buffer for erythrocyte lysis and bulk characterization
  • for the isolation of crypts from the connective tissues of mice

Biochem/physiol Actions

Ethylenediaminetetraacetic acid (EDTA) is used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors.
Ethylenediaminetetraacetic acid (EDTA) is used to treat patients poisoned with heavy metal ions. It functions as a chelator of the zinc ion in the active site of metalloproteases. EDTA inhibits other metal ion-dependent proteases such as calcium-dependent cysteine proteases. It might interfere with biological events which are metal ion-dependent. EDTA inhibits platelet aggregation and is the most preferred anticoagulant for platelet counts. It associates with other active agents to modulate microorganisms and biofilms, like citric acid, alcohol, antibiotics, polyhexamethylene biguanide (PHMB) quaternary ammonium compounds, and other antiseptics. EDTA is used as an anticoagulant for hematological testing, as it preserves the cellular components and morphology of blood cells. 

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Questo articolo
E651103695ED4S
description

99.0-102.0% (titration)

description

BioReagent, suitable for cell culture, 98.5-102.0%

description

purum, ≥98.0% (KT)

description

practical grade, ≥95%

assay

99.0-102.0% (titration)

assay

98.5-102.0%

assay

≥98.0% (KT)

assay

≥95%

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

200

form

crystalline

form

powder

form

powder or crystals

form

powder

solubility

H2O: soluble, clear, colorless

solubility

H2O: 160 mg/mL

solubility

H2O: 0.1 g/mL, clear

solubility

soluble, clear, colorless (32g plus 200ml of water)

reaction suitability

reagent type: chelator

reaction suitability

-

reaction suitability

reagent type: chelator

reaction suitability

reagent type: chelator


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Parola di avvertenza

Danger

Codici di pericolo

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2

Organi bersaglio

Respiratory Tract

Classe di stoccaggio

11 - Combustible Solids

Punto di infiammabilità (°F)

Not applicable

Punto di infiammabilità (°C)

Not applicable

DPI (dispositivi di protezione individuale)

dust mask type N95 (US), Eyeshields, Gloves



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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