F4765

Fluphenazine dihydrochloride

• Sinonimo/i: 4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol dihydrochloride
• Formula empirica (notazione di Hill): C₂₂H₂₆F₃N₃OS · 2HCl
• Numero CAS: 146-56-5
• Peso molecolare: 510.44
• NACRES: NA.77
• PubChem Substance ID: 57654184
• UNSPSC Code: 12352200
• EC Number: 205-674-1
• MDL number: MFCD00055212

Proprietà

• SMILES string: Cl.Cl.OCCN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1
• InChI: 1S/C22H26F3N3OS.2ClH/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29;;/h1-2,4-7,16,29H,3,8-15H2;2*1H
• InChI key: MBHNWCYEGXQEIT-UHFFFAOYSA-N
• Gene Information: human ... DRD1(1812), DRD2(1813), HRH1(3269)

Descrizione

General description

Fluphenazine may be useful for the treatment of schizophrenia.

Application

Fluphenazine dihydrochloride has been used:

• to study its effects as a drug on glioblastoma (GBM) cells
• in fluorescence-activated cell sorting (FACS) analysis, sorting and single-cell stress-survival experiments
• to study its exposure effects on learning and memory in adult rats

Biochem/physiol Actions

D₁/D₂ dopamine receptor antagonist; phenothiazine antipsychotic; H₁ histamine receptor antagonist.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Parola di avvertenza: Danger
• Codici di pericolo: H301,H360
• Avvertenze di sicurezza: P201 - P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral - Repr. 1A
• Classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable