MSTUD0175
MISSION® Synthetic microRNA Inhibitor, Mouse
mmu-miR-19b-3p
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Informazioni su questo articolo
NACRES:
NA.51
UNSPSC Code:
41105324
Prezzi e disponibilità al momento non sono disponibili
Servizio Tecnico
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Permettici di aiutartiQuality Segment
product line
MISSION®
form
solid
mature sequence
UGUGCAAAUCCAUGCAAAACUGA
Sanger mature/minor accession no.
microRNA accession no.
MI0000718
storage temp.
−20°C
General description
Individual synthetic microRNA inhibitors were designed using a proprietary algorithm, which is based on the work of Haraguchi, T, et al. and in collaboration with Dr. Hideo Iba, University of Tokyo. This algorithm utilizes the tough decoy (TuD) design. miRNA are known to regulate gene expression in a variety of manners, including translational repression, mRNA cleavage and deadenylation.
The MISSION synthetic miRNA Inhibitors are small, double-stranded RNA molecules designed to inhibit a specific mature miRNA. The miRNA inhibitors were designed using the mature miRNA sequence information from miRBase and are 2′-O-methylated RNA duplexes with a miRNA binding site on each strand. Optimal miRNA inhibition is provided after transfection due to the robust secondary structure of the inhibitor.
Two negative controls are available: Arabidopsis thaliana sequence (NCSTUD001) and Caenorhabditis elegans sequence (NCSTUD002)
The MISSION synthetic miRNA Inhibitors are small, double-stranded RNA molecules designed to inhibit a specific mature miRNA. The miRNA inhibitors were designed using the mature miRNA sequence information from miRBase and are 2′-O-methylated RNA duplexes with a miRNA binding site on each strand. Optimal miRNA inhibition is provided after transfection due to the robust secondary structure of the inhibitor.
- Long lasting inhibition at very low dosage
- Excellent resistance to cellular nucleases
- Custom synthesis available for a variety of species
Two negative controls are available: Arabidopsis thaliana sequence (NCSTUD001) and Caenorhabditis elegans sequence (NCSTUD002)
Other Notes
Based on miRBase V19
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
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Questo articolo | |
|---|---|
| description mmu-miR-19b-3p | description mmu-miR-147-3p |
| storage temp. −20°C | storage temp. −20°C |
| product line MISSION® | product line MISSION® |
| microRNA accession no. MI0000718 | microRNA accession no. MI0005482 |
| Sanger mature/minor accession no. | Sanger mature/minor accession no. |
| mature sequence UGUGCAAAUCCAUGCAAAACUGA | mature sequence GUGUGCGGAAAUGCUUCUGCUA |
| Quality Level 100 | Quality Level 100 |
Parola di avvertenza
Warning
Codici di pericolo
Avvertenze di sicurezza
Hazard Classifications
STOT RE 2 Inhalation
Organi bersaglio
Respiratory Tract
Classe di stoccaggio
11 - Combustible Solids
Che succede?
WGK 3
Punto di infiammabilità (°F)
Not applicable
Punto di infiammabilità (°C)
Not applicable
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