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Merck

Fumagillin-induced aseptic meningoencephalitis in a kidney transplant recipient with microsporidiosis.

Transplant infectious disease : an official journal of the Transplantation Society (2012-10-03)
A Audemard, M L Le Bellec, L Carluer, S Dargère, R Verdon, C Castrale, T Lobbedez, B Hurault de Ligny
ABSTRACT

Microsporidiosis is an opportunistic infection in organ transplant recipients and patients with other cellular immunodeficiency. Fumagillin is an effective treatment against Enterocytozoon bieneusi, one of the two main species causing the microsporidiosis involved in human diseases. We report the first case, to our knowledge, of a probable drug-induced aseptic meningoencephalitis, after administration of fumagillin in a kidney transplant recipient with microsporidiosis.

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Sigma-Aldrich
Fumagillin from Aspergillus fumigatus, ≥90%, powder