This product is stored refrigerated at 2-8°C and assigned a lot-specific retest date of approximately 7 years from the date of Quality Release. Products that, while considered stable, may be subject to degradation over time are assigned a periodic retest date to confirm quality. The lot-specific retest date is reported on the Certificate of Analysis. Please see the link below to review a lot-specific Certificate:
https://www.sigmaaldrich.com/product/mm/3301#product-documentation
3301
17β-Estradiol
≥97% (HPLC), solid, estrogenic hormone, Calbiochem
Synonyma:
17β-Estradiol, 17 beta Estradiol
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Vybrat velikost
Změnit zobrazení
| Vám/SKU | Dostupnost | Cena |
|---|---|---|
1 g | K dispozici k odeslání DNESodAreál Kühne+Nagel spol. s r.o. | 2 050,00 Kč |
400 g | Očekávané datum odeslání02. října 2026odAreál Kühne+Nagel spol. s r.o. | 409 900,00 Kč |
O této položce
Empirický vzorec (Hillův zápis):
C18H24O2
Číslo CAS:
Molekulová hmotnost:
272.38
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥97% (by assay)
Form:
solid
Storage condition:
OK to freeze
Technický servis
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Dovolte nám, abychom vám pomohliNázev produktu
17β-Estradiol, Most potent mammalian estrogenic hormone.
Quality Segment
description
RTECS - KG2975000
Merck USA index - 14, 3703
assay
≥97% (by assay)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white to off-white
solubility
ethanol: 5 mg/mL
shipped in
ambient
storage temp.
2-8°C
SMILES string
O[C@@H]1[C@@]2([C@H]([C@H]3[C@H](CC2)c4c(cc(cc4)O)CC3)CC1)C
InChI
1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
InChI key
VOXZDWNPVJITMN-ZBRFXRBCSA-N
General description
17β-Estradiol is a potent estrogen, a steroid hormone, involved in reproductive and endocrine functions in mammals. It binds to estrogen receptors (ERα and ERβ) to regulate gene expression, influencing reproductive functions such as the proliferation of the uterine endometrium, ovulation, and maintenance of pregnancy. Additionally, 17β-Estradiol is involved in modulating metabolic processes, including lipid metabolism and insulin sensitivity, and exerts neuroprotective effects in the central nervous system.
Application
17β-Estradiol has been used to treat primary rat cortical neurons, to investigate its effects on neuronal responses to interleukin (IL)-6 and soluble IL-6 receptor treatment. It has also been administered subcutaneously to ovariectomized female mice to investigate its effects on Crhr1 and Esr1 mRNA expression in the nucleus accumbens.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful & Carcinogenic / Teratogenic (E)
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Tato položka | |||
|---|---|---|---|
| description Most potent mammalian estrogenic hormone. | description BioReagent, powder, suitable for cell culture | description Pharmaceutical Secondary Standard; Certified Reference Material | description powder, γ-irradiated, suitable for cell culture |
| form solid | form powder | form - | form powder |
| assay ≥97% (by assay) | assay ≥98% (HPLC) | assay - | assay ≥98% (HPLC) |
| manufacturer/tradename Calbiochem® | manufacturer/tradename - | manufacturer/tradename - | manufacturer/tradename - |
| Quality Level 100 | Quality Level 200 | Quality Level 300 | Quality Level 200 |
| storage temp. 2-8°C | storage temp. room temp | storage temp. 2-30°C | storage temp. room temp |
| solubility ethanol: 5 mg/mL | solubility ethanol: 50 mg/mL, clear, colorless | solubility - | solubility ethanol: 1 mg/mL, clear, colorless to very faintly yellow |
Výstražné slovo
Danger
Kódy nebezpečí
Bezpečnostní pokyny
Skladovací třída
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Bod vzplanutí (°F)
Not applicable
Bod vzplanutí (°C)
Not applicable
Hazard Classifications
Aquatic Chronic 1 - Carc. 2 - ED ENV 1 - ED HH 1 - Lact. - Repr. 1A
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How long can it be stored in delivered dry form and what storage conditions are optimal.
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how long can you store the product at 4C after dissolving the product in ethanol ?
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When stored refrigerated at 2 - 8°C, de-gassed stock solutions are stable for up to 6 months. Alternatively, stock solutions may be stored frozen at -20°C for up to 3 months. Avoid repeated freeze/thaw cycles.
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