As provided, every batch of this product released has been tested for solubility in methanol at concentrations up to about 10 mg/mL. It is also known to be soluble in organic solvents, e.g., ethanol (2 mg/mL), DMSO (5 mg/mL), and dimethyl formamide (10 mg/mL). The optimal solvent may vary depending on the specific application.
F4767
Filipin III from Streptomyces filipinensis
≥85% (HPLC)
Synonyma:
Filimarisin
Přihlásit pro zobrazení organizačních a smluvních cen.
Vybrat velikost
Změnit zobrazení
| Vám/SKU | Dostupnost | Cena |
|---|---|---|
1 mg | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 4 600,00 Kč |
5 mg | Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti. | 18 400,00 Kč |
O této položce
Empirický vzorec (Hillův zápis):
C35H58O11
Číslo CAS:
Molekulová hmotnost:
654.83
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
eCl@ss:
32160703
4 600,00 Kč
Obraťte se na zákaznický servis a vyžádejte si informaci o dostupnosti.
Technický servis
Potřebujete pomoc? Náš tým zkušených odborníků je vám k dispozici.
Dovolte nám, abychom vám pomohliQuality Segment
assay
≥85% (HPLC)
form
powder
technique(s)
protein detection: suitable
mp
163-180 °C
solubility
methanol: 9.80-10.20 mg/mL, clear, colorless to yellow
antibiotic activity spectrum
fungi, yeast
mode of action
cell membrane | interferes
storage temp.
−20°C
SMILES string
CCCCCC(O)C1C(O)CC(O)CC(O)CC(O)CC(O)CC(O)CC(O)C(C)=C\C=C\C=C\C=C\C=C\C(O)C(C)OC1=O
InChI
1S/C35H58O11/c1-4-5-11-16-31(42)34-33(44)22-29(40)20-27(38)18-25(36)17-26(37)19-28(39)21-32(43)23(2)14-12-9-7-6-8-10-13-15-30(41)24(3)46-35(34)45/h6-10,12-15,24-34,36-44H,4-5,11,16-22H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,23-14-
InChI key
IMQSIXYSKPIGPD-BWJOQPJXSA-N
Application
Filipin has been used in a double staining procedure as a probe for the detection of lipoproteins in polyacrylamide gel and immobilized on nitrocellulose membranes.
Filipin has been used in a double staining procedure as a probe for the detection of lipoproteins in polyacrylamide gel and immobilized on nitrocellulose membranes. It is also widely used to localize and quantitate unesterified cholesterol by virtue of a specific fluorescent complex.
Biochem/physiol Actions
Filipin is a polyene macrolide antibiotic and antifungal. The antifungal mechanism of action may be due to altering membrane permeability and associated functions by binding to membrane sterols. Filipin inhibits prion protein (PrP) endocytosis and causes the release of PrP from the plasma membrane.
Other Notes
Filipin III is the major component of 8 isomeric components in filipin.
1 of 1
Tato položka | |||
|---|---|---|---|
| description ≥85% (HPLC) | description ≥98% (HPLC), film | description powder, BioReagent, suitable for cell culture | description Animal Component-free |
| assay ≥85% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay - |
| Quality Level 300 | Quality Level 300 | Quality Level 300 | Quality Level 200 |
| form powder | form film | form powder | form powder |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. - |
| solubility methanol: 9.80-10.20 mg/mL, clear, colorless to yellow | solubility DMSO: soluble, H2O: insoluble, methanol: soluble | solubility - | solubility H2O: 50 mg/mL, clear, colorless to faintly yellow |
| mp 163-180 °C | mp 288-291 °C | mp - | mp - |
Výstražné slovo
Warning
Kódy nebezpečí
Bezpečnostní pokyny
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Cílové orgány
Respiratory system
Skladovací třída
11 - Combustible Solids
Bod vzplanutí (°F)
Not applicable
Bod vzplanutí (°C)
Not applicable
PPE (osobní ochranné prostředky)
dust mask type N95 (US), Eyeshields, Gloves
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Good afternoon; I would be very grateful if you could clarify me which is the best solvent for filipin III (F4767) stock solution preparation. Product specification is different from product information (methanol; ethanol; DMSO..). Thank you in advance.
1 answer-
Helpful?
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