This product is intended for research use only. In vitro and in vivo studies have been conducted for research purposes. This product has been cited in a number of publications. Please see the link below to review the current peer reviewed papers:
https://www.sigmaaldrich.com/US/en/search/d047?focus=papers&page=1&perpage=30&sort=relevance&term=D047&type=citation_search
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D047
(±)-SKF-38393 hydrochloride
≥98% (HPLC), D1 dopamine receptor agonist, crystalline
Synonym(e):
(±)-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrochloride
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
100 mg | Ab HEUTE lieferbar | 263,00 € |
500 mg | Ab HEUTE lieferbar | 876,00 € |
1 g | Ab HEUTE lieferbar | 1.200,00 € |
Über diesen Artikel
Empirische Formel (Hill-System):
C16H17NO2 · HCl
CAS-Nummer:
Molekulargewicht:
291.77
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
eCl@ss:
32160702
Assay:
≥98% (HPLC)
Form:
crystalline
Storage condition:
desiccated, protect from light
Technischer Dienst
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Unterstützung erhaltenProduktname
(±)-SKF-38393 hydrochloride, crystalline, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
crystalline
storage condition
desiccated, protect from light
color
white
solubility
H2O: >5 mg/mL, aqueous base: soluble (unstable)
SMILES string
Cl.Oc1cc2CCNCC(c3ccccc3)c2cc1O
InChI
1S/C16H17NO2.ClH/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11;/h1-5,8-9,14,17-19H,6-7,10H2;1H
InChI key
YEWHJCLOUYPAOH-UHFFFAOYSA-N
Gene Information
human ... DRD1(1812)
Application
(±)-SKF-38393 hydrochloride has been used as a selective D1 receptor agonist as a part of dopaminergic treatment. It has also been used to study its effect on prolactin in male baboons.
Biochem/physiol Actions
(±)-SKF-38393 is a D1 dopamine receptor agonist. It is known to promote the production of glutamate in the hippocampus.
Disclaimer
This material is hygroscopic. Air-sensitive. Light-sensitive.
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Dieser Artikel | |||
|---|---|---|---|
| description crystalline, ≥98% (HPLC) | description - | description - | description solid |
| form crystalline | form - | form - | form solid |
| assay ≥98% (HPLC) | assay - | assay - | assay - |
| Quality Level 100 | Quality Level - | Quality Level - | Quality Level 100 |
| storage condition desiccated, protect from light | storage condition - | storage condition - | storage condition - |
| solubility aqueous base: soluble (unstable), H2O: >5 mg/mL | solubility - | solubility - | solubility DMSO: soluble, H2O: 7.5 mg/mL |
| color white | color - | color - | color white |
Signalwort
Warning
Gefahrencodes
Sicherheitshinweise
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklasse
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
PSA (Persönliche Schutzausrüstung)
dust mask type N95 (US), Eyeshields, Gloves
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is this crossed the preclinical studies as in invitro and invivo for parkinson's disease
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