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P1499

Pterostilben

≥97% (HPLC), apoptosis inducer, solid

Synonym(e):

Pterocarpus marsupium, 3,5-Dimethoxy-4′-hydroxystilbene, 4-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol

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Größe/SKUVerfügbarkeitPreis
10 mg

Voraussichtliches Versanddatum05. Oktober 2026vonSchnelldorf

315,00 €

Über diesen Artikel

Empirische Formel (Hill-System):
C16H16O3
CAS-Nummer:
Molekulargewicht:
256.30
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥97% (HPLC)
Form:
solid
Storage condition:
protect from light

315,00 €


Voraussichtliches Versanddatum05. Oktober 2026Details


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Produktname

Pterostilben, ≥97% (HPLC), solid

Quality Segment

assay

≥97% (HPLC)

form

solid

storage condition

protect from light

solubility

DMSO: >20 mg/mL, H2O: insoluble

storage temp.

2-8°C

SMILES string

COc1cc(OC)cc(\C=C\c2ccc(O)cc2)c1

InChI

1S/C16H16O3/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11,17H,1-2H3/b4-3+

InChI key

VLEUZFDZJKSGMX-ONEGZZNKSA-N

General description

Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene), an antioxidant is an analogue of resveratrol. It is present in blueberries, tree wood and some types of grapes.

Application

Pterostilbene has been used:
  • to investigate its anti-oxidative stress activities and the involvement of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-antioxidant response element (ARE) signaling pathway
  • to determine its effects on transcriptional activation of estrogen receptor-α (ERα) in hormone resistant breast cancer cells)
  • to study its effects on the cytotoxicity of 2-chloroethyl ethyl sulphide (CEES) in human epidermoid carcinoma cells (A-431) through MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide)viability assay

Biochem/physiol Actions

Pterostilbene exhibits antineoplastic properties in some of the malignancies, hence it is considered as an active anticancer agent. It has the ability to stimulate apoptosis and block the viability of cell in estrogen-receptor positive and negative breast cancer cell lines.
Antioxidant, antiproliferative, apoptosis inducer, antihyperglycemic, antidiabetic.

Disclaimer

Air-sensitive

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Dieser Artikel
PHL83261523310PHL80356
Astilbin phyproof® Reference Substance

PHL80356

Astilbin

description

≥97% (HPLC), solid

description

phyproof® Reference Substance

description

A cell-permeable methoxylated analog of Resveratrol that displays antioxidant, antiproliferative, and hypoglycemic properties.

description

phyproof® Reference Substance

assay

≥97% (HPLC)

assay

≥98.0% (HPLC)

assay

≥95% (HPLC)

assay

≥95.0% (HPLC)

form

solid

form

-

form

solid

form

-

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

H2O: insoluble, DMSO: >20 mg/mL

solubility

-

solubility

DMSO: 10 mg/mL, methanol: 10 mg/mL

solubility

-

storage condition

protect from light

storage condition

-

storage condition

OK to freeze, protect from light

storage condition

-


Piktogramme

CorrosionEnvironment

Signalwort

Danger

Gefahrencodes

Hazard Classifications

Aquatic Chronic 2 - Eye Dam. 1

Lagerklasse

11 - Combustible Solids

Was ist los?

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

PSA (Persönliche Schutzausrüstung)

dust mask type N95 (US), Eyeshields, Gloves



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Analysenzertifikate (COA)

Lot/Batch Number

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Fragen

  1. Actually we are using as a Analytical Standard for HPLC assay of Pterostilbene in RM and Final Product .Can we use this? if we can use How much purity we have to take for Calculation

    1 Antwort
    1. This product is tested for suitability in HPLC. The minimum purity of this material is 97%, and the maximum water content is 2.0 mol. These values are lot-specific and reported in the Certificate of Analysis. This material is not tested for use as an analytical standard. Suitability for this application would have to be determined by the end user. Please see the link below to review a sample or lot specific Certificate:
      https://www.sigmaaldrich.com/product/sigma/p1499#product-documentation

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