Merck

1.02975

SAFC

山梨醇FP液

FP, liquid, (sorbitol syrup, noncrystallizing), EMPROVE® ESSENTIAL, Ph. Eur., BP, NF, E 420

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别名:
D -山梨醇, D-山梨糖醇
经验公式(希尔记法):
C6H14O6
CAS号:
分子量:
182.17
Beilstein:
1721899
MDL编号:
E编号:
E420

Agency

BP
NF
Ph. Eur.

质量水平

蒸汽密度

<1 (vs air)

蒸汽压

<0.1 mmHg ( 25 °C)

产品线

EMPROVE® ESSENTIAL

形式

liquid
viscous liquid

pH值(酸碱度)

6 (20 °C in H2O, 50% solution)

mp

98-100 °C (lit.)

密度

1.3 g/cm3 at 20 °C

application(s)

liquid formulation
pharmaceutical

储存温度

2-30°C

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-JGWLITMVSA-N

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一般描述

Whether suspensions, emulsions or solutions – oral liquid dosage forms offer a number of advantages: They allow for individual dosing, are easy to swallow and are suitable for pediatric or geriatric applications. On the other hand, formulators face considerable challenges concerning solubility, API stability in aqueous systems, or taste that can often make a decisive difference. Our large product portfolio covers all excipients required for oral liquid formulation, as solvents and surfactants, flavors, ph adjustments and buffers, preservatives and viscosity enhancers.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Sorbitol is a sugar alcohol which is frequently used as sweetener in oral liquid pharmaceutical formulations, as well as bulking agent, sugar substitute or humectant in cosmetics and food and beverage. Non-crystallizing sorbitol is especially used as humectant and plasticizer for soft-gel capsules.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

WGK

WGK 1


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商品

Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric formulations.

相关内容

Developing formulations specifically for infants and children is increasingly important. To help you master these challenges effectively, we offer an extensive portfolio of well-established high-quality excipients and APIs for pediatric pharmaceutical formulations that are proven in practice.

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