1.16129

LiChrospher^® 100 RP-8 (5 µm)

HPLC sorbent

• Sinonimo/i: TM=["LiChrospher"] C8 sorbent for HPLC
• UNSPSC Code: 41115709
• NACRES: SB.52
• Particle size: 5 μm
• Matrix active group: C8 (RP8), C8 bonding phase
• Pore size: 100 Å pore size
• Matrix: fully porous particle

Proprietà

• Nome del prodotto: LiChrospher^® 100 RP-8 (5 µm),
• material: stainless steel column
• agency: suitable for USP L7
• product line: LiChrospher^®
• feature: endcapped: no
• analyte functional class(es): antibiotics, fat soluble vitamins, lipids, nutraceuticals and antioxidants, oils, pigments
• analyte chemical class(es): PCBs (aroclor identification), PFAS, aflatoxins, alcohols and aldehyde, alkaloids, amino acids, cannabinoids as tms derivatives, carotenoids, coloring compounds, essential oils, esters, fatty acids, flavonoids, ketones, metabolized steroids, nitrosamines, nucleosides, oligonucleotides, peptides, pesticides, phenols, phospholipids, phthalate esters, preservatives, proteins, steroids (cholesteryl esters), sulfonamides
• extent of labeling: 12.5% Carbon loading
• parameter: 60 °C max. temp.
• technique(s): HPLC: suitable, mass spectrometry (MS): suitable (Low - Medium)
• surface area: 350 m²/g
• matrix: fully porous particle
• matrix active group: C8 (RP8), C8 bonding phase
• particle size: 5 μm
• pore size: 100 Å pore size
• operating pH range: 2-7.5
• bulk density: 200‑400 kg/m³
• separation technique: reversed phase
• storage temp.: no temp limit

Descrizione

General description

LiChrospher^® RP-8 is a reliable and versatile traditionally produced spherical silica gel carrier with C-8 reversed phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds.

Application

• Development and validation of a HPLC-UV method for the determination in didanosine tablets.: This study presents a validated HPLC-UV method optimized using LiChrospher^® 100 RP-8 (5 µm) for analyzing didanosine in tablet formulations, offering a reliable tool for quality control in pharmaceutical environments (de Oliveira et al., 2005).


• Determination of steroid hormones in oral contraceptives by high-performance liquid chromatography.: Utilizes LiChrospher^® 100 RP-8 (5 µm) to effectively separate and quantify steroid hormones in oral contraceptive pills, demonstrating the column′s applicability in complex pharmaceutical analyses (Inês et al., 2002).


• Determination of fluoroquinolone residues in animal tissues by liquid chromatography.: Explores the use of LiChrospher^® 100 RP-8 (5 µm) for the sensitive detection of fluoroquinolone residues in animal tissues, highlighting its potential for food safety and veterinary medicine applications (Posyniak et al., 1999).


• Rapid and simple determination of oxytetracycline in chicken products.: Demonstrates the column′s efficiency in rapidly quantifying oxytetracycline residues in chicken, ensuring compliance with food safety standards (Furusawa, 1999).


• Crocheted ETFE-reactor for on-line post-column photoderivatization of diclofenac in high-performance liquid chromatography.: Describes an innovative application involving LiChrospher^® 100 RP-8 (5 µm) in a post-column reactor setup to enhance the detection sensitivity of diclofenac, underlining the column′s versatility in advanced analytical techniques (Kuhlmann et al., 1997).

Analysis Note

Application test: passes test
Pressure: ≤ 45 bar
Theoretical Plates (N/m) (Toluene): ≥ 60000
Capacity factor (Toluene): ≥ 0.7
stability testing (performance): passes test
separation factor (PTH-Lysine/PHB-Propyl-Ester, selectivity test): 1.20 - 1.55
separation factor (Naphthalene/Digitoxigenin, selectivity test): 3.5 - 4.7
separation factor (PTH-Lysine/Digitoxigenin, selsctivity test): 1.70 - 2.25
Particle Size (d10): 4.8 - 5.5 µm
Particle Size (d50): 6.5 - 7.5 µm
Particle Size (d90): 9.0 - 10.5 µm

Legal Information

LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• Che succede?: nwg
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable