- Titanocene difluorides with improved cytotoxic activity.
Titanocene difluorides with improved cytotoxic activity.
Inorganic chemistry (2010-01-09)
Silvia Eger, Timo A Immel, James Claffey, Helge Müller-Bunz, Matthias Tacke, Ulrich Groth, Thomas Huhn
PMID20055428
ABSTRACT
Titanocene difluorides can be obtained by halide metathesis of the respective titanocene dichlorides with trimethyltin fluoride (Me(3)SnF), giving access to a new class of cytotoxic active substances. Furthermore, an improved method for the synthesis of diaryl-substituted titanocene dichlorides is presented.
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