- Iridium-catalyzed enantioselective hydrogenation of alpha,beta-unsaturated carboxylic acids.
Iridium-catalyzed enantioselective hydrogenation of alpha,beta-unsaturated carboxylic acids.
Journal of the American Chemical Society (2008-06-13)
Shen Li, Shou-Fei Zhu, Can-Ming Zhang, Song Song, Qi-Lin Zhou
PMID18547043
ABSTRACT
A highly efficient iridium-catalyzed hydrogenation of alpha,beta-unsaturated carboxylic acids has been developed by using chiral spiro-phosphino-oxazoline ligands, affording alpha-substituted chiral carboxylic acids in exceptionally high enantioselectivities and reactivities.
MATERIALI