- NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts.
NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts.
Blood (2017-07-25)
Christopher R Marlein, Lyubov Zaitseva, Rachel E Piddock, Stephen D Robinson, Dylan R Edwards, Manar S Shafat, Zhigang Zhou, Matthew Lawes, Kristian M Bowles, Stuart A Rushworth
PMID28733324
ABSTRACT
Improvements in the understanding of the metabolic cross-talk between cancer and its microenvironment are expected to lead to novel therapeutic approaches. Acute myeloid leukemia (AML) cells have increased mitochondria compared with nonmalignant CD34
MATERIALI
Numero di prodotto
Marchio
Descrizione del prodotto