- Protein kinase- and lipase inhibitors of inositide metabolism deplete IP
Protein kinase- and lipase inhibitors of inositide metabolism deplete IP
Cellular signalling (2017-10-19)
Subu Surendran Rajasekaran, Christopher Illies, Stephen B Shears, Huanchen Wang, Thais S Ayala, Joilson O Martins, Elisabetta Daré, Per-Olof Berggren, Christopher J Barker
PMID29042286
ABSTRACT
Inositol pyrophosphates have emerged as important regulators of many critical cellular processes from vesicle trafficking and cytoskeletal rearrangement to telomere length regulation and apoptosis. We have previously demonstrated that 5-di-phosphoinositol pentakisphosphate, IP
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Sigma-Aldrich
U-73122, U-73122, CAS 112648-68-7, inhibits agonist-induced phospholipase C activation (IC50 = 1-2.1 µM) in human platelets and neutrophils.
Sigma-Aldrich
Anti-IP6K1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
Sigma-Aldrich
IP6K Inhibitor, The IP6K Inhibitor, also referenced under CAS 519178-28-0, controls the biological activity of IP6K.