RNF146 Inhibits Excessive Autophagy by Modulating the Wnt-β-Catenin Pathway in Glutamate Excitotoxicity Injury.

RNF146 Inhibits Excessive Autophagy by Modulating the Wnt-β-Catenin Pathway in Glutamate Excitotoxicity Injury.

Frontiers in cellular neuroscience (2017-03-23)

Yuefan Yang, Peng Luo, Haoxiang Xu, Shuhui Dai, Wei Rao, Cheng Peng, Wenke Ma, Jiu Wang, Hongyu Xu, Lei Zhang, Sai Zhang, Zhou Fei

PMID28321181

ABSTRACT

Glutamate induced excitotoxicity is common in diverse neurological disorders. RNF146 as an E3 ubiquitin ligase protects neurons against excitotoxicity

MATERIALI

Numero di prodotto

Marchio

Descrizione del prodotto

P0067

Sigma-Aldrich

Anti-p62/SQSTM1, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution

L8918

Sigma-Aldrich

Anti-LC3, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution

SAB1306537

Sigma-Aldrich

ANTI-BECLIN1-BH3 DOMAIN antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution