8.55129

NovaSyn^® TG PAP RESIN

Novabiochem^®

特性

• 品質水準: 200
• 製品種目: NovaSyn^® TG; Novabiochem^®
• フォーム: beads
• 反応適合性: reaction type: Fmoc solid-phase peptide synthesis
• メーカー／製品名: Novabiochem^®
• アプリケーション: peptide synthesis
• 官能基: amine
• 保管温度: 2-8°C

詳細

詳細

NovaSyn TG PAP resin contains an acid cleavable linkage between the polystyrene matrix and the PEG chain. Treatment of peptides prepared on this resin with TFA/thioanisole (95:5) for 12 hours or TMSBr/TFA/thioanisole (1:94:5) for 60 minutes releases a fully deprotected peptide possessing a PEG-chain attached to the C-terminus ^[1]. Such peptide-PEG conjugates can be used directly as immunogens, without the need for a carrier protein. The peptide-PEG conjugates are also highly soluble and provide an effective solution to insoluble peptides.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Literature references

^[1] W. Rapp in ′Combinatorial Peptide and Nonpeptide Libraries′, G. Jung (Eds), Vch, 1996, pp. 425.

アナリシスノート

Colour (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/g
Swelling Volume (in CH₂Cl₂): lot specific result

法的情報

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable