567021

Simvastatin Sodium Salt

HMG-CoA reductase inhibitor, (Beige solid)

• 동의어(들): L-Type Calcium Channel Blocker VI, Simvastatin, Sodium Salt - Calbiochem
• Linear Formula: C25H39O6.Na
• UNSPSC 코드: 51111800
• NACRES: NA.32

속성

• 제품 이름: Simvastatin, Sodium Salt - Calbiochem,
• 양식: (Beige solid)
• Quality Level: 100
• 저장 조건: OK to freeze
• solubility: soluble (DMSO (100 mg/ml), Ethanol (25 mg/ml), or H2O (5 mg/ml))
• 저장 온도: −20°C

설명

일반 설명

Carboxylate form of Simvastatin (Cat. No. 567020) that is active in whole cells and in cell-free assays. A lipophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that blocks Ras function through inhibition of farnesylation. Also inhibits glucose-induced Ca2+-signaling and insulin secretion by blocking L-type Ca2+ channels in rat islet β-cells. Inhibits cell proliferation of human smooth muscle cells. Note: This product is supplied in an active form; no treatment with NaOH in ethanol is required for its activation.