The amount of iron in this product is not determined.
F6879
Ferritin from human spleen
Type V, 10 μg/mL in 0.15 M NaCl, 10 mM Tris, pH 8.0, containing 0.1% sodium azide
다음으로 건너뛰기
생물학적 소스
human spleen
Quality Level
무균
sterile-filtered
유형
Type V
양식
liquid
포장
vial of 2 μg
농도
10 μg/mL in 0.15 M NaCl, 10 mM Tris, pH 8.0, containing 0.1% sodium azide
저장 온도
2-8°C
유전자 정보
human ... FTH1(2495), FTL(2512)
1 of 4
이 품목 | F7879 | F6754 | F5012 |
|---|---|---|---|
| biological source human spleen | biological source horse spleen | biological source human liver | biological source rabbit |
| concentration 10 μg/mL in 0.15 M NaCl, 10 mM Tris, pH 8.0, containing 0.1% sodium azide | concentration 10 mg/mL in 0.15 M NaCl | concentration 10 μg/mL | concentration - |
| form liquid | form liquid | form liquid | form liquid |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
| Gene Information human ... FTH1(2495), FTL(2512) | Gene Information horse ... FTL(100051593) | Gene Information human ... FTH1(2495), FTL(2512), FTMT(94033) | Gene Information human ... FTH1(2495) |
애플리케이션
Ferritin is an iron storage protein that plays a central role in iron metabolism, and may be elevated in inflammatory or malignant diseases. It has been used in studies as an indicator of body iron supply, but may prove inaccurate in in the presence of chronic inflammation.
생화학적/생리학적 작용
A ubiquitous iron storage protein that plays a key role in iron metabolism. It serves as an intracellular iron reserve (particularly in spleen, liver, intestinal mucosa, and bone marrow) and functions in iron detoxification. Studies have shown that ferritin iron incorporation is mediated by a ferroxidase activity associated with ferritin H subunits and a nucleation center associated with ferritin L subunits. Release of iron from ferritin has an essential role in iron-dependent lipid peroxidation and may contribute to free radical-induced cell damage in vivo. Therefore, by binding iron, ferritin may function as an antioxidant.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Rune J Ulvik et al.
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 133(8), 845-849 (2013-04-25)
A low supply of iron in the diet may result in iron deficiency and mild iron-deficiency anaemia in healthy individuals. Women are more susceptible than men because of menstrual iron loss. We compared the effect of a low dose of
Zonghuan Lu et al.
Journal of structural biology, 168(3), 388-395 (2009-08-18)
The goal of time-resolved cryo-electron microscopy is to determine structural models for transient functional states of large macromolecular complexes such as ribosomes and viruses. The challenge of time-resolved cryo-electron microscopy is to rapidly mix reactants, and then, following a defined
Sajid Soofi et al.
Lancet (London, England), 382(9886), 29-40 (2013-04-23)
Powders containing iron and other micronutrients are recommended as a strategy to prevent nutritional anaemia and other micronutrient deficiencies in children. We assessed the effects of provision of two micronutrient powder formulations, with or without zinc, to children in Pakistan.
Oner Ozdogan et al.
Acta cardiologica, 68(3), 299-305 (2013-07-26)
Cardiovascular involvement is the leading cause of mortality in patients with beta-thalassaemia major (beta-TM). This cross-sectional study was performed to evaluate the earlier cardiac damage in beta-TM by echocardiography, before left ventricular (LV) systolic dysfunction was observed. The study population
Opposite extremes in hepcidin status between the US and Japan.
Takeshi Nakanishi et al.
The American journal of medicine, 126(5), e11-e11 (2013-04-16)
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