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A6969

Sigma-Aldrich

L-Arginine monohydrochloride

not synthetic, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sinónimos:
(S)-(+)-Arginine hydrochloride, (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride
Empirical Formula (Hill Notation):
C6H14N4O2 · HCl
Número de CAS:
Peso molecular:
210.66
Beilstein:
3631658
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.26

Nivel de calidad

200

agency

USP/NF
meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

ensayo

98.5-101.0%

formulario

powder

calidad

meets EP, JP, USP testing specifications

technique(s)

cell culture | mammalian: suitable

impurezas

endotoxin, tested

color

white

mp

226-230 °C

solubilidad

water: 100 mg/mL, clear, colorless

densidad

1.42 g/cm3 at 20 °C

trazas de anión

chloride (Cl-): 16.58-17.00%
sulfate (SO42-): ≤0.020%

trazas de catión

As: ≤1 ppm
Fe: ≤10 ppm
NH4+: ≤0.02%
heavy metals: ≤10 ppm

application(s)

pharmaceutical (small molecule)

SMILES string

Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1

InChI key

KWTQSFXGGICVPE-WCCKRBBISA-N

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Categorías relacionadas

Aplicación

L-Arginine monohydrochloride has been used in mouse pancreas perfusion experiments. It has also been used as a component of SILAC medium.

Envase

100 g in poly bottle
25 kg in poly drum
1 kg in poly bottle

Acciones bioquímicas o fisiológicas

L-Arginine is a dibasic, semi-essential amino acid. It acts as a precursor for creatinine and is a natural constituent of most of the dietary proteins.
Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

Certificado de Análisis

Certificado de origen

The role of somatostatin in GLP-1-induced inhibition of glucagon secretion in mice
Anne Orgaard
Diabetologia, 60(9), 1731-1739 (2017)
Lorenzo Galluzzi K
Cell-wide Metabolic Alterations Associated with Malignancy (2014)
Nina C Hubner et al.
Methods (San Diego, Calif.), 53(4), 453-459 (2010-12-28)
Large-scale proteomic screens are increasingly employed for placing genes into specific pathways. Therefore generic methods providing a physiological context for protein-protein interaction studies are of great interest. In recent years many protein-protein interactions have been determined by affinity purification followed
J. P. Felix D'Mello
Amino Acids in Human Nutrition and Health (2012)
Élie Lambert et al.
Molecular & cellular proteomics : MCP, 19(5), 808-827 (2020-03-04)
HNF4α is a nuclear receptor produced as 12 isoforms from two promoters by alternative splicing. To characterize the transcriptional capacities of all 12 HNF4α isoforms, stable lines expressing each isoform were generated. The entire transcriptome associated with each isoform was

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