C8667

Cholesterol

Sigma Grade, ≥99%

• Sinónimos: 3β-Hydroxy-5-cholestene, 5-Cholesten-3β-ol
• Empirical Formula (Hill Notation): C₂₇H₄₆O
• Número de CAS: 57-88-5
• Peso molecular: 386.65
• Beilstein: 1915888
• Número de EC: 200-353-2
• Número MDL: MFCD00003646
• eCl@ss: 39023139
• ID de la sustancia en PubChem: 24893094
• NACRES: NA.77

Propiedades

• origen biológico: sheep wool
• grado: Sigma Grade
• ensayo: ≥99%
• formulario: powder
• bp: 360 °C (lit.)
• mp: 147-149 °C (lit.)
• solubilidad: water: soluble 0.00003 g/L at 20 °C
• densidad: 1.067 g/mL at 25 °C (lit.)
• enviado en: ambient
• temp. de almacenamiento: −20°C
• SMILES string: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
• InChI key: HVYWMOMLDIMFJA-DPAQBDIFSA-N
• Gene Information: human ... POLA1(5422) , TOP2A(7153) ; rat ... Ar(24208) , Polb(29240)

Descripción

Aplicación

Standard for chromatography

Cholesterol was used to prepare immune-stimulating complexes to enhance cellular and humoral responses. It was incorporated in animal feed to study the effect of cholesterol-rich diet.

Envase

500 mg in poly bottle

1, 5, 25, 100 g in poly bottle

Acciones bioquímicas o fisiológicas

Cholesterol is a lipid that makes up about 20-25% of the structural components of the cell membranes. It determines the fluidity and permeability of the membrane, making it permeable to water but not to ions and protons. Cholesterol also regulates the functions of the transporters and signaling proteins present on the plasma membrane. The major sites of cholesterol synthesis are small intestine and liver.

Major component of all biological membranes; ~25% of total brain lipid is cholesterol.

Nota de preparación

Cholesterol monohydrate yields a clear, colorless to faint yellow solution in hot alcohol. It is also soluble in acetone, dioxane, ethyl acetate, benzene, petroleum ether, oils, fats, and in aqueous solutions of bile salts. Solutions should be protected from light.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• WGK: WGK 1
• Punto de inflamabilidad F: Not applicable
• Punto de inflamabilidad C: Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)