Merck
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SML0010

Sigma-Aldrich

LY-334370 hydrochloride hydrate

≥98% (HPLC), powder

Synonym(s):
4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide hydrochloride hydrate
Empirical Formula (Hill Notation):
C21H22FN3O · HCl · xH2O
Molecular Weight:
387.88 (anhydrous basis)
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.77

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

powder

color

white to tan

solubilidad

H2O: ≥5 mg/mL (warmed)

emisor

Eli Lilly

temp. de almacenamiento

2-8°C

SMILES string

Cl.CN1CCC(CC1)c2c[nH]c3ccc(NC(=O)c4ccc(F)cc4)cc23

InChI

1S/C21H22FN3O.ClH/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15;/h2-7,12-14,23H,8-11H2,1H3,(H,24,26);1H

InChI key

DGPDGAPZTPSHBL-UHFFFAOYSA-N

Aplicación

LY-334370 hydrochloride hydrate may be used to study 5-HT 1F-mediated cell signaling.

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

LY-334370 hydrochloride is a selective 5-HT1F receptor agonist.
LY-334370 modulates the transmission in the mouse trigeminal system and inhibits the neuronal responses within rat Sp5C by inhibiting c-Fos activation. It shows efficacy in aborting migraine attacks.

Características y beneficios

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 3

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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