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Merck

5.09455

Etomoxir

≥98% (HPLC), liquid, CPT-1 inhibitor, Calbiochem®

Synonym(s):

InSolution Etomoxir, R(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt hydrate

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About This Item

Empirical Formula (Hill Notation):
C15H18ClO4 · Na
CAS Number:
Molecular Weight:
320.74
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

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Product Name

Etomoxir, InSolution, ≥98%, 50 mM aqueous solution, shown to inhibit carnitine palmitoyltransferase (CPT)-1 and DGAT activity

Quality Level

Assay

≥98% (HPLC)

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles
protect from light

storage temp.

−70°C

SMILES string

[Na+].Clc1ccc(cc1)OCCCCCC[C@]2(OC2)C(=O)[O-]

InChI

1S/C15H19ClO4.Na/c16-12-5-7-13(8-6-12)19-10-4-2-1-3-9-15(11-20-15)14(17)18;/h5-8H,1-4,9-11H2,(H,17,18);/q;+1/p-1/t15-;/m1./s1

InChI key

RPACBEVZENYWOL-XFULWGLBSA-M

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1 of 4

This Item
236020E19055.06081
assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

liquid

form

solid

form

powder

form

liquid

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

Calbiochem®

storage temp.

−70°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−70°C

storage condition

OK to freeze, protect from light, avoid repeated freeze/thaw cycles

storage condition

OK to freeze, protect from light

storage condition

-

storage condition

OK to freeze, avoid repeated freeze/thaw cycles, desiccated (hygroscopic), protect from light

General description

A cell-permeable, irreversible, and stereospecific compound that is shown to inhibit carnitine palmitoyltransferase (CPT)-1 and DGAT activity in the mitochondria of rat heart H9c2 myoblastic cells at a concentration of 1-80 µM and 40 µM, respectively.

Biochem/physiol Actions

Primary Target
CPT1

Packaging

Packaged under inert gas

Physical form

A 50 mM (2 mg/118 µL) solution of Etomoxir (Cat. No. 236020) in H₂O.

Preparation Note

Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.

Other Notes

Xu, F.Y., et al. 2003. J. Lipid Res.44, 415.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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