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ADRA2A

adrenoceptor alpha 2A

Synonimy:
ADRA2, ADRA2R, ADRAR, ALPHA2AAR, ZNF32
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(150) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
  • Mouse(11551) adrenergic receptor, alpha 2a
  • Rat(25083) adrenoceptor alpha 2A
  • domestic guinea pig(100135475) adrenergic receptor, alpha 2a
  • chicken(428980) adrenergic, alpha-2A-, receptor
  • sheep(100170317) adrenoceptor alpha 2A
  • Domestic Rabbit(100009424) adrenoceptor alpha 2A
  • Zebrafish(266750) adrenergic, alpha-2A-, receptor
  • dog(486888) adrenoceptor alpha 2A
  • domestic cat(664736) adrenoceptor alpha 2A
  • sheep(101117291) adrenoceptor alpha 2A
  • naked mole-rat(101723298) adrenoceptor alpha 2A
  • cow(282135) adrenergic, alpha-2A-, receptor

Custom & Knockdown Gene Products

Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Clonidine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Clonidine hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Clonidine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Xylazine hydrochloride, ≥99.0% (HPLC),
Gatunek
human
Clonidine hydrochloride, solid,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
1-Naphthylmethylamine, 97%,
Gatunek
rat
1,2,3,4-Tetrahydroisoquinoline, 95%,
Gatunek
rat, human
Idazoxan hydrochloride, ,
Gatunek
human
Yohimbine hydrochloride, ≥98% (HPLC), powder,
Gatunek
human
RX 821002 hydrochloride, solid, ≥98% (HPLC),
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-ADRA2A antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence
Anti-Adrenergic Receptor α-2A antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-ADRA2A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
canine, human, mouse, rat
Zastosowanie
ELISA
immunocytochemistry

immunofluorescence
Anti-α2A Adrenergic Receptor antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, pig, rat
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Mianserin hydrochloride, ,
Gatunek
human
Agmatine sulfate salt, ≥97%, powder,
Gatunek
human

Small Molecule - Mixed Agonist/Antagonist

Numer produktu
Opis
Gatunek
UK 14,304, ,
Gatunek
human
(−)-Norepinephrine, ≥98%, crystalline,
Gatunek
human, rat
Haloperidol, powder,
Gatunek
human, rat
Clozapine, ,
Gatunek
human, rat

Proteins

Numer produktu
Opis
Gatunek
ChemiSCREEN Preparat błony ludzkiego receptora adrenergicznego α2A, Human alpha2A GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Gatunek
human