GRM6
glutamate receptor, metabotropic 6
Synonimy:
CSNB1B, GPRC1F, MGLUR6, mGlu6
Gatunek:
Human GRM6 (2916), Mouse Grm6 (108072), Rat Grm6 (24419), domestic guinea pig Grm6 (100722389), naked mole-rat Grm6 (101717017), cow GRM6 (529656), domestic cat GRM6 (101097449), dog GRM6 (481452)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(2916) Summary: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq, Feb 2012]
- Mouse(108072) glutamate receptor, metabotropic 6
- Rat(24419) glutamate receptor, metabotropic 6
- domestic guinea pig(100722389) glutamate receptor, metabotropic 6
- naked mole-rat(101717017) glutamate receptor, metabotropic 6
- cow(529656) glutamate receptor, metabotropic 6
- domestic cat(101097449) glutamate receptor, metabotropic 6
- dog(481452) glutamate receptor, metabotropic 6
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Agonist
Numer produktu
Opis
Gatunek
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Gatunek
rat, human
Small Molecule - Antagonist
Numer produktu
Opis
Gatunek
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Gatunek
rat, human
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-GRM6 antibody produced in mouse, clone 1A11, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
western blot
Anty-GRM6, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Przeciwciało przeciwko metabotropowemu receptorowi glutaminianu 6, Chemicon®, from rabbit,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-MGLUR6 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Mixed Agonist/Antagonist
Numer produktu
Opis
Gatunek
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Gatunek
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Gatunek
rat, human