MAPK10
mitogen-activated protein kinase 10
Synonimy:
JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK
Gatunek:
Human MAPK10 (5602), Mouse Mapk10 (26414), Rat Mapk10 (25272), Horse MAPK10 (100052608), Domestic Rabbit MAPK10 (100337999), domestic guinea pig Mapk10 (100718766), Zebrafish mapk10 (569698), sheep MAPK10 (101120665), dog MAPK10 (478464), domestic cat MAPK10 (101101463) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(5602) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(26414) mitogen-activated protein kinase 10
- Rat(25272) mitogen activated protein kinase 10
- Horse(100052608) mitogen-activated protein kinase 10
- Domestic Rabbit(100337999) mitogen-activated protein kinase 10
- domestic guinea pig(100718766) mitogen-activated protein kinase 10
- Zebrafish(569698) mitogen-activated protein kinase 10
- sheep(101120665) mitogen-activated protein kinase 10
- dog(478464) mitogen-activated protein kinase 10
- domestic cat(101101463) mitogen-activated protein kinase 10
- naked mole-rat(101712980) mitogen-activated protein kinase 10
- cow(537631) mitogen-activated protein kinase 10
- chicken(422592) mitogen-activated protein kinase 10
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
ANTI-MAPK10 antibody produced in mouse, clone 3A3-1A8, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
western blot
Przeciwciało anty-JNK3, klon 2O10P2, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Monoclonal Anti-MAPK10 antibody produced in mouse, clone 3B9, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
western blot
Przeciwciało anty-Mapk10 wytwarzane u królików, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot
western blot
Przeciwciało anty-JNK3/SAPK1b, klon C05T, królicze monoklonalne, culture supernatant, clone C05T, from rabbit,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Small Molecule - Inhibitor
Proteins
Numer produktu
Opis
Gatunek
Białko JNK3/SAPK1b, aktywne, 10 µg, Active, N-terminal His6 tagged, recombinant, full length human JNK3/SAPK1b, for use in Kinase Assays.,
Gatunek
human
Białko JNK3/SAPK1b, nieaktywne, 50 g, Unactive, N-terminal His6-tagged recombinant human JNK3/SAPK1b, for use in Kinase Assays.,
Gatunek
human
esiRNA
Numer produktu
Opis
Gatunek