D5146

Diazolidinyl urea

≥95%

• Synonim(y): 1-[1,3-Bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea, Diazolidinylurea, N-Hydroxymethyl-N-[1,3-di(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-N′-hydroxymethylurea, N-[1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-N,N′-bis(hydroxymethyl)urea
• Wzór empiryczny (zapis Hilla): C₈H₁₄N₄O₇
• Numer CAS: 78491-02-8
• Masa cząsteczkowa: 278.22
• NACRES: NA.22
• PubChem Substance ID: 57654106
• UNSPSC Code: 12352100
• EC Number: 278-928-2
• MDL number: MFCD03547942
• Assay: ≥95%
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥95%
• form: powder
• functional group: amine, hydroxyl
• storage temp.: 2-8°C
• SMILES string: OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O
• InChI: 1S/C8H14N4O7/c13-1-9-7(18)10(2-14)5-6(17)12(4-16)8(19)11(5)3-15/h5,13-16H,1-4H2,(H,9,18)
• InChI key: SOROIESOUPGGFO-UHFFFAOYSA-N

Opis

General description

Diazolidinyl urea is urea derivative that is commonly used as a preservative and antimicrobial agent in cosmetics and personal care products.

Application

• Impact of cosmetic preservatives on skin cells: A study examined the effects of various cosmetic preservatives, including Diazolidinyl Urea, on healthy human skin cells, highlighting the cellular responses and potential implications for skin health (Głaz et al., 2023).
• Formaldehyde releasers in personal care: An extensive clinical review discussed allergic contact dermatitis caused by formaldehyde and formaldehyde releasers such as Diazolidinyl Urea, providing insights into allergic reactions and safety concerns in dermatological practice (Goossens and Aerts, 2022).
• Carcinogenic potential of cosmetic ingredients: Research on potential carcinogens in makeup cosmetics included Diazolidinyl Urea, emphasizing the safety and regulatory aspects concerning its use in cosmetic formulations (Balwierz et al., 2023).
• Patch testing for allergen sensitivity: A study integrated Diazolidinyl Urea in a patch test series to evaluate skin sensitization and allergic reactions in patients, aiding in the assessment of its allergenic potential (Bizjak et al., 2022).

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H319
• Ostrzeżenia: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• PPE (środki ochrony indywidualnej): dust mask type N95 (US), Eyeshields, Faceshields, Gloves