1.08178

Trifluoroacetic acid

for protein sequence analysis

• Synonim(y): TFA
• Wzór liniowy: CF₃COOH
• Numer CAS: 76-05-1
• Masa cząsteczkowa: 114.02
• UNSPSC Code: 12352106
• NACRES: NA.21
• EC Index Number: 200-929-3
• MDL number: MFCD00004169
• Beilstein/REAXYS Number: 742035
• Assay: ≥99.7% (acidimetric)
• Form: liquid

Właściwości

• vapor density: 3.9 (vs air)
• Quality Segment: 200
• vapor pressure: 97.5 mmHg ( 20 °C)
• assay: ≥99.7% (acidimetric)
• form: liquid
• impurities: ≤0.02% Water (Karl Fischer)
• refractive index: n20/D 1.3 (lit.)
• pH: 1 (10 g/L in H₂O)
• bp: 72.4 °C (lit.)
• mp: −15.4 °C (lit.)
• solubility: soluble 10 g/mL
• density: 1.489 g/mL at 20 °C (lit.)
• storage temp.: 2-30°C
• SMILES string: OC(C(F)(F)F)=O
• InChI: 1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)
• InChI key: DTQVDTLACAAQTR-UHFFFAOYSA-N

Opis

Application

Trifluoroacetic acid (TFA) can be used as an ion-pairing agent in a reverse-phase HPLC system to separate peptides because it enhances peak resolution. It also has low absorption detection wavelengths and is relatively volatile and can be easily removed. For the majority of peptide separations, TFA has been used at concentrations ranging from 0.05 to 0.1%(6.5-13 mM).

Analysis Note

Assay (acidimetric): ≥ 99.7 %
Identity (IR-spectrum): passes test
Density (d 20 °C/20 °C): about 1.53
Boiling point: about 72 °C
Water (according to Karl Fischer): ≤ 0.02 %

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08,GHS05,GHS07
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H314,H332,H361d,H412
• Ostrzeżenia: P202 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Klasa składowania: 8A - Combustible corrosive hazardous materials
• supp_hazards: EUH071
• Hazard Classifications: Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Repr. 2 - Skin Corr. 1A