17-218

Zestaw do testu aktywacji Ras

• Synonim(y): Test aktywności Ras
• UNSPSC Code: 12161503
• NACRES: NA.84
• eCl@ss: 32161000

Właściwości

• manufacturer/tradename: Upstate^®
• Quality Segment: 100
• technique(s): activity assay: suitable
• NCBI accession no.: NM_001085049.1, NM_012219.3
• UniProt accession no.: O14807
• shipped in: dry ice
• Gene Information: human ... MRAS(22808)

Opis

General description

Muscle RAS oncogene homolog (MRAS) plays a key role in cardiovascular diseases. The MRAS gene codes for a member of the ras superfamily of GTP-binding proteins. MRAS is found in all tissues, particularly in the cardiovascular system. It is involved in signal transduction, including cell growth and differentiation.

Packaging

Kit capacity: 30 assays

Analysis Note

This kit precipitated Ras-GTP from HeLa cell lysates that had been loaded with GTPγS. The precipitated Ras-GTP was detected by western immunoblot using 1μg/ml anti-Ras, clone RAS10

Other Notes

Ras Assay Reagent (Raf-1 RBD, agarose) (Cat.# 14-278)

Anti-Ras, clone RAS10 (Cat.# 05-516)

100X GTPγS, 10mM (Cat.# 20-176)

100X GDP, 100mM (Cat.# 20-177)

Mg2+ Lysis/Wash Buffer, 5X (Cat.# 20-168)

Replaces: SGT435

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS05,GHS09
• Słowo ostrzegawcze: Danger
• Klasa składowania: 10 - Combustible liquids
• Co się dzieje?: WGK 3
• Kody zagrożeń: H318,H410,EUH430
• Ostrzeżenia: P201 - P202 - P273 - P280 - P305 + P351 + P338 - P391 - P405 - P501
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1