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540223
Purmorphamine
≥98% (HPLC), liquid, Hedgehog signaling activator, Calbiochem
Synonim(y):
InSolution Purmorphamine, Purmorphamine
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| Rozmiar/SKU | Dostępność | Cena netto |
|---|---|---|
5 mg | Przewidywany termin wysyłki09 listopada 2026zKuehne + Nagel Sp. z o.o. | 1020,00 zł |
Informacje o tej pozycji
Wzór liniowy:
C31H32N6O2
UNSPSC Code:
12352116
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
liquid
Storage condition:
OK to freeze, desiccated (hygroscopic), protect from light
1020,00 zł
Przewidywany termin wysyłki09 listopada 2026Szczegóły
Pomoc techniczna
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Pozwól nam pomócNazwa produktu
Purmorphamine, InSolution, ≥98%, 50 mM in DMSO, induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells
Quality Segment
assay
≥98% (HPLC)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic), protect from light
storage temp.
−20°C
General description
A cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells (EC50 = 1 µM) and in MC3T3-E1 lineage-committed preosteoblasts. Also shown to induce transdifferentiation in pre-adipocytes and myoblasts. Its effects are reported to be synergistic with bone morphogenetic protein-4 (BMP-4). Reported to induce osteogenesis by activation of the Hedgehog signaling pathway.
Purmorphamine is a cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells.
Application
InSolution Purmorphamine, CAS 483367-10-8, is a provided as a 50 mM solution in DMSO. Induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 & lineage-committed preosteoblasts MC3T3-E1.
Packaging
Packaged under inert gas
Physical form
A 50 mM (5 mg/192 µl) solution of Purmorphamine (Cat. No. 540220) in DMSO.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
Wu, X., et al. 2004. Chem. Biol.11, 1229.
Wu, X., et al. 2002. J. Am. Chem. Soc.124, 14520.
Wu, X., et al. 2002. J. Am. Chem. Soc.124, 14520.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
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Ta pozycja | |||
|---|---|---|---|
| description InSolution, ≥98%, 50 mM in DMSO, induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells | description A cell-permeable activator of Hedgehog signaling that induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 (EC50 = 1 µM). | description ≥98% (HPLC) | description ≥99.0% (TLC) |
| form liquid | form solid | form powder | form solid |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥99.0% (TLC) |
| manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® | manufacturer/tradename - | manufacturer/tradename - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. - |
| storage condition protect from light, OK to freeze, desiccated (hygroscopic) | storage condition protect from light, OK to freeze | storage condition - | storage condition - |
Słowo ostrzegawcze
Warning
Kody zagrożeń
Hazard Classifications
Muta. 2
Klasa składowania
10 - Combustible liquids
Co się dzieje?
WGK 2
Temperatura zapłonu (°F)
188.6 °F - closed cup
Temperatura zapłonu (°C)
87 °C - closed cup
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