P3C030C00

Pellicon^® 3 Cassette with Ultracel^® Membrane

filtration area 88 cm², NMWCO 30 kDa, holdup volume, 1.5 mL (in feed channel)

• Synonim(y): Pellicon^® 3 Cassette with Ultracel^® 30 kDa Membrane, C Screen, 88 cm², Pellicon^® 3 Ultracel^® Membrane Cassette, Pellicon^® 3 Ultrafiltration Cassette
• UNSPSC Code: 41104903
• NACRES: NB.24
• eCl@ss: 32031602

Właściwości

• Quality Segment: 400
• material: TPE seal, composite regenerated cellulose (CRC) membrane, polypropylene , polypropylene cap (for end), polypropylene screen
• sterility: non-sterile
• product line: Pellicon^®
• feature: holdup volume 1.5 mL (in feed channel)
• manufacturer/tradename: Pellicon^®
• parameter: 2.75 bar max. inlet pressure (40 psi) at 50 °C, 30 psi max. reverse press. exposure at 25 °C (for 24 hours), 4-6 L/min-m² recirculation rate, 40 psi max. transmembrane pressure at 4-50 °C, 5.5 bar max. inlet pressure (80 psi) at 40 °C, 5.5 bar max. transmembrane pressure (80 psig) at 30 °C, 6.9 bar max. inlet pressure (100 psi), 80 psi max. transmembrane pressure at 4-40 °C
• technique(s): analytical sample preparation: suitable, buffer exchange: suitable, protein purification: suitable (concentration), tangential flow filtration (TFF): suitable
• H: 0.8 cm (0.33 in.)
• L: 20.6 cm (8.1 in.)
• W: 5.6 cm (2.2 in.)
• filtration area: 88 cm²
• membrane area: 88 cm²
• gravimetric extractables: ≤1500 mg/m²
• matrix: Ultracel^® (Membrane)
• pore size: 30 kDa NMWCO
• pH: 2-13
• application(s): mAb; recombinant protein
• shipped in: ambient

Opis

General description

The Pellicon^® 3 Cassette with Ultracel^® membrane is a high performance tangential flow filtration (TFF) device designed to support efficient ultrafiltration and diafiltration of therapeutic antibodies and other biologics. This cassette is manufactured for high product recovery, reliable flux performance, and robust cleanability. It reduces processing time while maintaining product quality. Its durable construction enables operation under demanding process conditions, including elevated pressures, and temperatures, making it an ideal choice for today′s high-titer bioprocessing applications.

Application

Pellicon^® 3 Cassettes with Ultracel^® 30 kD Membrane C screenis designed for filtration processes that require maximum mass transfer andflux. From process development through commercial production, these cassettesdeliver reliable performance across various filtration applications, including:

• Monoclonal antibodies (mAbs)
• Recombinant and non-recombinant proteins
• Vaccine process streams

Features and Benefits

• Rugged & reliable – ideally suited for today′s more demanding filtration processes
• High performance – produces excellent resolution, yields and back-pressure resistance
• Optimum product recovery – thanks to proven membrane technology
• Void-free technology – leading-edge membranes resolve virtually any separation challenge
• Defect-free, superior adhesion – Ultracel^®uses composite membranes cast on a microporous substrate
• Automated manufacturing – delivers unbeatable performance, consistency and reliability
• Easy installation & care – simple to install and maintain

Analysis Note

Gravimetric Extractables: after 24 hours in water at controlled room temperature

Other Notes

These products are manufactured in a facility which adheres to FDA Good Manufacturing Practices.

Legal Information

Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany

ULTRACEL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 10 - Combustible liquids