04573

Thiamine hydrochloride

tested according to Ph. Eur.

• Synonim(y): Thiamio hydrochloridum, Aneurine hydrochloride, Vitamin B₁ hydrochloride
• Wzór empiryczny (zapis Hilla): C₁₂H₁₇ClN₄OS · HCl
• Numer CAS: 67-03-8
• Masa cząsteczkowa: 337.27
• NACRES: NA.26
• PubChem Substance ID: 329747946
• eCl@ss: 34058006
• UNSPSC Code: 12352209
• EC Number: 200-641-8
• MDL number: MFCD00012780
• Beilstein/REAXYS Number: 3851771

Właściwości

• biological source: synthetic
• Quality Segment: 200
• agency: tested according to Ph. Eur.
• assay: 98.5-101.0% anhydrous basis
• form: solid
• mp: 250 °C (dec.) (lit.)
• solubility: alcohol: soluble 1 gm in 100 ml (95%), alcohol: soluble 1 gm in 315 ml (Absolute), glycerol: soluble 1 gm in 18 ml, water: soluble 1 g/mL, benzene: insoluble, chloroform: insoluble, diethyl ether: insoluble, hexane: insoluble, methanol: very soluble, propylene glycol: soluble
• storage temp.: 2-8°C
• SMILES string: CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]
• InChI: 1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1
• InChI key: DPJRMOMPQZCRJU-UHFFFAOYSA-M

Opis

Application

Thiamine hydrochloride has been used as a keratin salts medium supplement for culturing log-phase fungus. It has also been used as a supplement of VB medium the minimal medium of Vogel and Bonner.

Biochem/physiol Actions

Thiamine hydrochloride is a cheap, non-toxic and efficient catalyst for the synthesis of amidoalkyl naphthols. It inhibits the production of shikonin derivatives by suspension cultures of Lithospermum erythrorhizon. Additionally, thiamine hydrochloride addition to apple juice concentrates reduces its patulin content.

Thiamine hydrochloride is a hydrochloride salt form of thiamine (Vitamin B₁). It is crucial for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H319
• Ostrzeżenia: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Klasa składowania: 11 - Combustible Solids
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): Eyeshields, Gloves, type N95 (US)