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64306

S-Methyl methanethiosulfonate

purum, ≥98.0% (GC)

Synonim(y):

S-Methyl thiomethanesulfonate, MMTS

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Rozmiar/SKUDostępnośćCena netto
1 mL
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219,00 zł
10 mL
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1020,00 zł

Informacje o tej pozycji

Wzór liniowy:
CH3SO2SCH3
Numer CAS:
Masa cząsteczkowa:
126.20
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-970-0
Beilstein/REAXYS Number:
1446059
MDL number:
Assay:
≥98.0% (GC)

219,00 zł


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grade

purum

Quality Segment

assay

≥98.0% (GC)

refractive index

n20/D 1.513

bp

69-71 °C/0.4 mmHg (lit.)

solubility

chloroform: 750mg + 5 ml Chloroform mg/mL, colorless to light greenish-yellow

density

1.337 g/mL at 20 °C, 1.337 g/mL at 25 °C (lit.)

functional group

disulfide

storage temp.

2-8°C

SMILES string

CSS(C)(=O)=O

InChI

1S/C2H6O2S2/c1-5-6(2,3)4/h1-2H3

InChI key

XYONNSVDNIRXKZ-UHFFFAOYSA-N

Application


  • Modification of Thiol Enzymes: S-methyl methanethiosulfonate (MMTS) offers a unique method for the modification of thiol enzymes and redox-regulated proteins, providing potential applications in biochemical research focused on enzyme regulation and redox biology (Makarov et al., 2019).

  • Sensor Development for Protease Activity: S-methyl methanethiosulfonate is used as a blocking reagent on the structural transitions of papain-like cysteine proteases, which supports its utility in sensor development, allowing for the detection and analysis of protease activity in various biological processes (Markovic et al., 2023).

  • Agricultural Pathogen Control: Research evaluating S-methyl methanethiosulfonate as a late blight inhibitor highlights its potential as a broad-range toxin against plant pathogens, suggesting applications in agriculture for the management of crop diseases (Joller et al., 2020).

Other Notes

Methylsulfenylating agent with many applications; For the α-methylsulfenylation of cyclic ketones; Methyl disulfides from thiols; selective, reversible inactivation of enzymes

Disclaimer

may discolor to yellow on storage
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Ta pozycja
208795390267
description

purum, ≥98.0% (GC)

description

97%

description

99%

assay

≥98.0% (GC)

assay

97%

assay

99%

Quality Level

200

Quality Level

200

Quality Level

200

solubility

chloroform: 750mg + 5 ml Chloroform mg/mL, colorless to light greenish-yellow

solubility

DMF: soluble 1:1, water: soluble 1:5, chloroform: soluble 200 ul per mL, clear, faintly yellow-green

solubility

-

bp

69-71 °C/0.4 mmHg (lit.)

bp

69-71 °C/0.4 mmHg (lit.)

bp

-

storage temp.

2-8°C

storage temp.

-

storage temp.

-

density

1.337 g/mL at 20 °C, 1.337 g/mL at 25 °C (lit.)

density

1.337 g/mL at 25 °C (lit.)

density

-


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PPE (środki ochrony indywidualnej)

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Piktogramy

Skull and crossbones

Słowo ostrzegawcze

Danger

Kody zagrożeń

Hazard Classifications

Acute Tox. 3 Oral - Skin Sens. 1

Klasa składowania

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Co się dzieje?

WGK 3



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Questions

1–3 of 3 Questions  
  1. What is the temperature and pH range that this product effectively blocks thiol groups?

    1 answer
    1. S-Methyl methanethiosulfonate (MMTS) is commonly used to modify and block thiol groups in proteins. To achieve effective blocking of thiol groups with MMTS, the following ranges should be considered:
      pH: Reactions with MMTS are typically performed in buffers with a pH range of 7-8.
      Temperature: Blocking of Thiols can be carried out at room temperature (25 °C).
      A literature search is encouraged to determine the best conditions for specific applications.

      Helpful?

  2. What is the solubility of Product 64306, S-Methyl methanethiosulfonate?

    1 answer
    1. Product 64306, S-Methyl methanethiosulfonate, is practically insoluble in water. It is soluble in methylene chloride. Several references do report that S-Methyl methanethiosulfonate is soluble in isopropanol at a 200mM concentration.  References are provided below: 1.  Yan, W., et al., "Quantitative Proteomic Analysis to Profile Dynamic Changes in the Spatial Distribution of Cellular Proteins", in Methods in Molecular Biology, Vol. 432: Organelle Proteomics, pp. 389-401 (Humana Press, 2008).2.  Sadowski, P.G., et al., Quantitative proteomic approach to study subcellular localization of membrane proteins.  Nature Protocols, 1, 1778-1789 (2006).

      Helpful?

  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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