69480

N-Methyl-N-trimethylsilylacetamide

derivatization grade (GC derivatization), LiChropur^™, ≥97.0% (GC)

• Synonim(y): MSA
• Wzór empiryczny (zapis Hilla): C₆H₁₅NOSi
• Numer CAS: 7449-74-3
• Masa cząsteczkowa: 145.27
• UNSPSC Code: 23151816
• NACRES: NA.22
• PubChem Substance ID: 329761691
• EC Number: 231-217-0
• Beilstein/REAXYS Number: 506975
• MDL number: MFCD00040758
• eCl@ss: 32150319

Właściwości

• grade: derivatization grade (GC derivatization)
• Quality Segment: 100
• assay: ≥97.0% (GC)
• form: liquid
• quality: LiChropur^™
• reaction suitability: reagent type: derivatization reagent; reaction type: Silylations
• technique(s): HPLC: suitable, LC/MS: suitable, gas chromatography (GC): suitable, ion chromatography: suitable
• refractive index: n20/D 1.439
• bp: 159-161 °C (lit.)
• density: 0.904 g/mL at 20 °C (lit.)
• storage temp.: −20°C
• SMILES string: CN(C(C)=O)[Si](C)(C)C
• InChI: 1S/C6H15NOSi/c1-6(8)7(2)9(3,4)5/h1-5H3
• InChI key: QHUOBLDKFGCVCG-UHFFFAOYSA-N

Opis

General description

N-Methyl-N-trimethylsilylacetamide is a trialkyl-silyl reagent and a versatile derivatizing agent used in gas chromatography (GC).

Application

N-Methyl-N-trimethylsilylacetamide may be used as a derivatizing reagent for the following:       

• Quantification of the carbohydrate intermediates in glycation systems using gas chromatography coupled to mass spectrometry technique.       
• Characterization of damaged products of thymine and cytosine formed by the exposure to UV light in a hydrogen peroxide solution using gas chromatography/mass spectrometry with scan mode and selected ion monitoring mode.

Other Notes

Powerful silylating agent for polar compounds

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS02
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H226
• Hazard Classifications: Flam. Liq. 3
• Klasa składowania: 3 - Flammable liquids
• WGK: WGK 3
• Temperatura zapłonu (°F): 118.4 °F - closed cup
• Temperatura zapłonu (°C): 48.0 °C - closed cup
• PPE (środki ochrony indywidualnej): Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter