97622

2-Mercaptoethanol

derivatization grade (HPLC), LiChropur^™, ≥99.0% (GC)

• Synonim(y): β-Mercaptoethanol, 2-Hydroxyethylmercaptan, BME, Thioethylene glycol
• Wzór liniowy: HSCH₂CH₂OH
• Numer CAS: 60-24-2
• Masa cząsteczkowa: 78.13
• UNSPSC Code: 23151817
• NACRES: NA.05
• PubChem Substance ID: 329770550
• EC Number: 200-464-6
• Beilstein/REAXYS Number: 773648
• MDL number: MFCD00004890

Właściwości

• grade: derivatization grade (HPLC)
• Quality Segment: 100
• vapor density: 2.69 (vs air)
• vapor pressure: 1 mmHg ( 20 °C)
• assay: ≥99.0% (GC)
• form: liquid
• quality: LiChropur^™
• expl. lim.: 18 %
• concentration: 14.3 M (pure liquid)
• technique(s): HPLC: suitable, LC/MS: suitable, ion chromatography: suitable
• refractive index: n20/D 1.500 (lit.), n20/D 1.500-1.502
• bp: 157 °C (lit.)
• density: 1.114 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: OCCS
• InChI: 1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2
• InChI key: DGVVWUTYPXICAM-UHFFFAOYSA-N

Opis

General description

2-Mercaptoethanol is a thiol compound showing growth promoting properties on mouse lymphoma L1210 cells in vitro. It also enhances viability, blast transformation and antibody formation in lymphocyte cultures.

Application

BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.

suitable for derivatisation of Amine groups

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06,GHS08,GHS05,GHS09
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H301 + H331,H310,H315,H317,H318,H361f,H373,H410
• Ostrzeżenia: P273 - P280 - P301 + P310 - P302 + P352 + P310 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1A - STOT RE 2 Oral
• Narządy docelowe: Liver,Heart
• Klasa składowania: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Temperatura zapłonu (°F): 165.2 °F - closed cup
• Temperatura zapłonu (°C): 74 °C - closed cup