A4673

Albendazole

analytical standard, ≥98%

• Synonim(y): Methyl 5-(propylthio)-2-benzimidazolecarbamate
• Wzór empiryczny (zapis Hilla): C₁₂H₁₅N₃O₂S
• Numer CAS: 54965-21-8
• Masa cząsteczkowa: 265.33
• NACRES: NA.24
• PubChem Substance ID: 329770859
• UNSPSC Code: 41116107
• EC Number: 259-414-7
• MDL number: MFCD00083232
• eCl@ss: 25140904

Właściwości

• grade: analytical standard
• Quality Segment: 100
• assay: ≥98%
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• SMILES string: CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1
• InChI: 1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
• InChI key: HXHWSAZORRCQMX-UHFFFAOYSA-N

Opis

General description

Chemical structure: benzimidazole

Albendazole is a benzimidazole derivative used for the treatment of human gastrointestinal helmintiasis. It inhibits microtubule and blocks the glucose uptake that causes depletion of glycogen stores and lowering formation of adinosine triphosphate (ATP) in the larval and adult stages of susceptible parasite.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Albendazole may be used as a reference standard for the determination of albendazole and its major metabolites, albendazole sulphoxide and albendazole sulphone by high-performance liquid chromatography (HPLC) method in mice plasma.

Biochem/physiol Actions

Binds to tubulin and inhibits microtubule assembly.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08,GHS09
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H361d,H373,H410
• Ostrzeżenia: P202 - P260 - P273 - P280 - P308 + P313 - P391
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral
• Narządy docelowe: Adrenal gland,Blood,male reproductive organs,spleen
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): Eyeshields, Gloves, type N95 (US)