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C1900000

Chlorpromazine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonim(y):

2-Chloro-10-(3-dimethylaminopropyl)phenothiazine hydrochloride, CPZ, Largactil

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Gabaryty przesyłkiSKUDostępnośćCena netto
150 mg
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670,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C17H19ClN2S · HCl
Numer CAS:
69-09-0
Masa cząsteczkowa:
355.33
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329774913
MDL number:
MFCD00012654
Beilstein/REAXYS Number:
3779989

670,00 zł

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grade

pharmaceutical primary standard

API family

chlorpromazine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl[H].CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13

InChI

1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H

InChI key

FBSMERQALIEGJT-UHFFFAOYSA-N

Gene Information

human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)

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Ta pozycja
1125006BP85631679
Chlorpromazine hydrochloride European Pharmacopoeia (EP) Reference Standard

C1900000

Chlorpromazine hydrochloride

Chlorpromazine hydrochloride United States Pharmacopeia (USP) Reference Standard

USP

1125006

Chlorpromazine hydrochloride

Chlorpromazine hydrochloride British Pharmacopoeia (BP) Reference Standard

BP856

Chlorpromazine hydrochloride

Chlorpromazine hydrochloride VETRANAL®, analytical standard

Supelco

31679

Chlorpromazine hydrochloride

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

analytical standard

manufacturer/tradename

EDQM

manufacturer/tradename

USP

manufacturer/tradename

BP

manufacturer/tradename

-

format

neat

format

neat

format

neat

format

neat

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical
pharmaceutical small molecule

application(s)

forensics and toxicology
pharmaceutical (small molecule)

Gene Information

human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)

Gene Information

human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)

Gene Information

human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)

Gene Information

human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)

API family

chlorpromazine

API family

chlorpromazine

API family

chlorpromazine

API family

-

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Substitute for benzidine, o-dianisidine, and o-tolidine in the determination of microquantities of hemoglobin and peroxidase.

Biochem/physiol Actions

Chlorpromazine demonstrates cytotoxic and antiproliferative activity against leukemic cells, but does not affect the viability of normal lymphocytes.
Phenothiazine antipsychotic; D2 dopamine receptor antagonist, H1 histamine receptor antagonist; inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.
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pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301,H330

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 3 Oral

Klasa składowania

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certyfikaty analizy (CoA)

Lot/Batch Number

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Jessica M D'Amico et al.
Journal of neurophysiology, 109(6), 1473-1484 (2012-12-12)
In animals, the recovery of motoneuron excitability in the months following a complete spinal cord injury is mediated, in part, by increases in constitutive serotonin (5-HT2) and norepinephrine (α1) receptor activity, which facilitates the reactivation of calcium-mediated persistent inward currents
Cristiane Flora Villarreal et al.
Pharmacology, biochemistry, and behavior, 103(3), 678-683 (2012-11-28)
In recent years, evidence that sensitization of primary afferent nociceptors is an important event associated with chronic pain has been accumulating. The present study aimed to evaluate the participation of the prostaglandin and sympathetic components in the long-lasting sensitization of
Jessica J W Broeders et al.
Toxicology in vitro : an international journal published in association with BIBRA, 27(3), 1057-1064 (2013-02-05)
The extrapolation of in vitro to in vivo toxicity data is a challenge. Differences in sensitivity between cell systems may be due to intrinsic properties of the cell but also because of differences in exposure. In this study, the cytotoxicity
Meghan J McFadden et al.
Chembiochem : a European journal of chemical biology, 15(16), 2411-2419 (2014-09-23)
Disruption of calmodulin (CaM)-based protein interactions has been touted as a potential means for modulating several disease pathways. Among these is SOX9, which is a DNA binding protein that is involved in chrondrocyte differentiation and regulation of the hormones that
Sébastien Anthérieu et al.
Hepatology (Baltimore, Md.), 57(4), 1518-1529 (2012-11-24)
Drugs induce cholestasis by diverse and still poorly understood mechanisms in humans. Early hepatic effects of chlorpromazine (CPZ), a neuroleptic drug known for years to induce intrahepatic cholestasis, were investigated using the differentiated human hepatoma HepaRG cells. Generation of reactive
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Numer pozycji handlu globalnego

SKUNUMER GTIN
C190000004061833468296

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