Merck
All Photos(3)

E4884

Sigma-Aldrich

Ethylenediaminetetraacetic acid disodium salt dihydrate

ACS reagent, 99.0-101.0%

Synonym(s):
Edetate disodium salt dihydrate, Disodium ethylenediaminetetraacetate dihydrate, EDTA disodium salt, Edathamil, EDTA-Na2, Sequestrene Na2
Empirical Formula (Hill Notation):
C10H14N2Na2O8 · 2H2O
CAS Number:
Molecular Weight:
372.24
Beilstein:
3900609
Numer EC:
Identyfikator substancji w PubChem:
NACRES:
NA.77

Poziom jakości

200

klasa czystości

ACS reagent

próba

99.0-101.0%

forma

solid

zanieczyszczenia

≤0.005% Insoluble matter
≤0.1% Nitrilotriacetic acid ([HOCOCH2]3N)

pH

4.0-6.0 (25 °C, 5%)

mp

248 °C (dec.) (lit.)

rozpuszczalność

H2O: 100 g/L at 20 °C

ślady kationów

Fe: ≤0.01%
heavy metals (as Pb): ≤0.005%

temp. przechowywania

room temp

SMILES string

O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2

InChI key

OVBJJZOQPCKUOR-UHFFFAOYSA-L

Looking for similar products? Visit Product Comparison Guide

Opis ogólny

EDTA is a chelator of divalent cations. It inhibits enzymes, such as metalloproteases, that require divalent cations for activity.

Zastosowanie

Ethylenediaminetetraacetic acid disodium salt dehydrate has been used as a component:
  • of radioimmunoprecipitation assay buffer (RIPA buffer) for preparation of C2C12 mouse skeletal myoblasts whole cell lysate
  • of lysis buffer and IgG resin wash and equilibration buffer for the purification of human proteasome regulatory particles (RPs)
  • of M-buffer for the isolation of human cardiomyocyte progenitor cells (CMPCs) from fetal heart

Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.

Opakowanie

100, 500 g in poly bottle

Działania biochem./fizjol.

Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood. EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia. EDTA along with tetracycline serves as a root conditioning agent and provides relief in gum infection. EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis. Calcium disodium EDTA administration is effective in slowing down the progression of chronic kidney disease. It also enhances the antimicrobial functionality of lysozyme and improves shelf life of cheese.

piktogramy

Exclamation markHealth hazard

Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

Zwroty wskazujące środki ostrożności

Klasyfikacja zagrożeń

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - STOT RE 2 Inhalation

Organy docelowe

Respiratory Tract

Kod klasy składowania

11 - Combustible Solids

WGK

WGK 2

Temperatura zapłonu °F

Not applicable

Temperatura zapłonu °C

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service