39286

Hydroxystilbamidine bis(methanesulfonate)

suitable for fluorescence, ≥96.0% (HPLC)

• Synonim(y): 2-Hydroxystilbene-4,4′-dicarboxamidine bis(methanesulfonate), Fluoro-Gold
• Wzór empiryczny (zapis Hilla): C₁₈H₂₄N₄O₇S₂
• Numer CAS: 223769-64-0
• Masa cząsteczkowa: 472.54
• NACRES: NA.32
• PubChem Substance ID: 57649893
• UNSPSC Code: 41116100
• MDL number: MFCD01863083

Właściwości

• Quality Segment: 100
• assay: ≥96.0% (HPLC)
• form: powder
• fluorescence: λ_ex 340 nm nm in phosphate buffer (pH 6.0 with DNA)
• suitability: suitable for fluorescence
• storage temp.: 2-8°C
• SMILES string: CS(O)(=O)=O.CS(O)(=O)=O.NC(=N)c1ccc(cc1)\C=C\c2ccc(cc2O)C(N)=N
• InChI: 1S/C16H16N4O.2CH4O3S/c17-15(18)12-5-2-10(3-6-12)1-4-11-7-8-13(16(19)20)9-14(11)21;2*1-5(2,3)4/h1-9,21H,(H3,17,18)(H3,19,20);2*1H3,(H,2,3,4)/b4-1+;;
• InChI key: YGNSQKCULHSJDC-HFPMQDOPSA-N

Opis

General description

Hydroxystilbamidine bis (methanesulfonate), also known as Fluoro-Gold, is a retrograde fluorescent tracer. Chemically, Hydroxystilbamidine is a weak base and can cross cell membranes in its uncharged form.

A few properties of Hydroxystilbamidine bis (methanesulfonate) are:

• Intense Fluorescence.
• Extensive filling of dendrites.
• High Resistance to fading.
• No uptake by undamaged fibers.
• No diffusion from labelled cells.
• Highly compatible with other neuro-histochemical techniques.

Application

Hydroxystilbamidine bis (methanesulfonate) or Fluoro-Gold (FG) is used to label neurons and investigate the early effects of hearing loss. It is used to study morphological features of extensive axonal projections within the CNS by labelling the cells.

Hydroxystilbamidine bis(methanesulfonate), a fluorescent retrograde tracer (axonal transport), is used for neural mapping in microanatomical research.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves